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Midazolam Pharmacokinetics in Morbidly Obese Patients Following Semi-Simultaneous Oral and Intravenous Administration: A Comparison with Healthy Volunteers

Author
BRILL, Margreke J. E1 2 ; VAN RONGEN, Anne1 2 ; HOUWINK, Aletta P. I3 ; BURGGRAAF, Jacobus1 4 ; VAN RAMSHORST, Bert5 ; WIEZER, René J5 ; VAN DONGEN, Eric P. A3 ; KNIBBE, Catherijne A. J1 2
[1] Division of Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands
[2] Department of Clinical Pharmacy, St. Antonius Hospital, Koekoekslaan 1, 3435 CM Nieuwegein, Netherlands
[3] Department of Anaesthesiology, Intensive Care and Pain Management, St. Antonius Hospital, Nieuwegein, Netherlands
[4] Centre for Human Drug Research (CHDR), Leiden, Netherlands
[5] Department of Surgery, St. Antonius Hospital, Nieuwegein, Netherlands
Source

Clinical pharmacokinetics. 2014, Vol 53, Num 10, pp 931-941, 11 p ; ref : 50 ref

CODEN
CPKNDH
ISSN
0312-5963
Scientific domain
Pharmacology drugs
Publisher
Adis International, Auckland
Publication country
New Zealand
Document type
Article
Language
English
Keyword (fr)
Etat nutritionnel Etude comparative Homme Hypnotique Individu sain Midazolam Obésité Pharmacocinétique Psychotrope Sédatif Voie intraveineuse Voie orale Dérivé de la benzodiazépine Trouble de la nutrition
Keyword (en)
Nutritional status Comparative study Human Hypnotic Healthy subject Midazolam Obesity Pharmacokinetics Psychotropic Sedative Intravenous administration Oral administration Benzodiazepine derivatives Nutrition disorder
Keyword (es)
Estado nutricional Estudio comparativo Hombre Hipnótico Individuo sano Midazolam Obesidad Farmacocinética Psicotropo Sedante Vía intravenosa Vía oral Benzodiazepina derivado Trastorno nutricíon
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B22 Metabolic diseases / 002B22B Obesity

Discipline
General pharmacology Metabolic diseases
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
28934754

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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