Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits
- Author
- SILVERWOOD, Richard J1 2 3 ; HOLMES, Michael V3 4 ; CASAS, Juan P1 10 ; DUDBRIDE, Frank1 2 3 ; DALE, Caroline E1 ; LAWLOR, Debbie A5 6 ; WHITTAKER, John C1 7 ; SMITH, George Davey5 6 ; LEON, David A1 ; PALMER, Tom8 ; KEATING, Brendan J9 ; ZUCCOLO, Luisa5 6
[1] Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
[2] Centre for Statistical Methodology, London School of Hygiene and Tropical Medicine, London, United Kingdom
[3] Bloomsbury Centre for Genetic Epidemiology and Statistics, London School of Hygiene and Tropical Medicine, London, United Kingdom
[4] Department of Epidemiology and Public Health, University College London, London, United Kingdom
[5] MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom
[6] School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
[7] Genetics, R & D, GlaxoSmithKline, Stevenage, United Kingdom
[8] Division of Health Sciences, University of Warwick, Warwick, Coventry, United Kingdom
[9] Center for Applied Genomics, Abramson Research Center, Children's Hospital of Philadelphia, Philadelphia, PA, United States
[10] Institute of Cardiovascular Science, University College London, London, United Kingdom
Alcohol-ADH1B Consortium - Source
International journal of epidemiology. 2014, Vol 43, Num 6, pp 1781-1790, 10 p ; ref : 29 ref
- CODEN
- IJEPBF
- ISSN
- 0300-5771
- Scientific domain
- Hygiene and public health, epidemiology, occupational medicine
- Publisher
- Oxford University Press, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- Mendelian randomization alcohol consumption cardiovascular disease causal inference instrumental variables local average treatment effects
- Keyword (fr)
- Analyse statistique Appareil circulatoire Application Boisson alcoolisée Cause Consommation Dépistage Ethanol Génotype Inférence Méthode statistique Pathologie de l'appareil circulatoire Randomisation Santé publique Traitement Typage Variable instrumentale
- Keyword (en)
- Statistical analysis Circulatory system Application Alcoholic beverage Cause Consumption Medical screening Ethanol Genotype Inference Statistical method Cardiovascular disease Randomization Public health Treatment Typing Instrumental variable
- Keyword (es)
- Análisis estadístico Aparato circulatorio Aplicación Bebida alcohólica Causa Consumo Descubrimiento Etanol Genotipo Inferencia Método estadístico Aparato circulatorio patología Aleatorización Salud pública Tratamiento Tipificación Variable instrumental
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B30 Public health. Hygiene-occupational medicine / 002B30A Public health. Hygiene / 002B30A03 Prevention and actions
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B30 Public health. Hygiene-occupational medicine / 002B30A Public health. Hygiene / 002B30A11 Miscellaneous
- Discipline
- Public health. Hygiene-occupational medicine
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 29086450
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1093/ije/dyu187 
https://dx.doi.org/10.1093/ije/dyu187
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