Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3
- Author
- PATEL, S. A. A1 ; BHAMBRA, U1 ; CHARALAMBOUS, M. P1 ; DAVID, R. M1 ; EDWARDS, R. J2 ; LIGHTFOOT, T3 ; BOOBIS, A. R2 ; GOODERHAM, N. J1
[1] Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London SW7 2AZ, United Kingdom
[2] Experimental Medicine and Toxicology, Department of Medicine, Imperial College London, London W12 0NN, United Kingdom
[3] Department of Health Sciences, University of York, York YO10 5DD, United Kingdom - Source
British journal of cancer. 2014, Vol 111, Num 12, pp 2287-2296, 10 p ; ref : 1 p.1/4
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Author keyword
- colorectal cancer cytochrome P450 immunohistochemistry inflammation microRNA
- Keyword (fr)
- Cancer colorectal Cancérologie Cytochrome P450 DNA Facteur transcription STAT3 Immunohistochimie Inflammation Interférence ARN Interleukine 6 Micro ARN Méthylation Cytochrome P450 1B1 Cytochrome P450 2E1 Anatomopathologie Cancer Cytokine Enzyme Pathologie de l'appareil digestif Pathologie de l'intestin Pathologie du côlon Pathologie du rectum Silence expression génique Tumeur maligne
- Keyword (en)
- Colorectal cancer Cancerology Cytochrome P450 DNA Transcription factor STAT3 Immunohistochemistry Inflammation RNA interference Interleukin 6 Micro RNA Methylation Cytochrome P450 1B1 Anatomic pathology Cancer Cytokine Enzyme Digestive diseases Intestinal disease Colonic disease Rectal disease Gene silencing Malignant tumor
- Keyword (es)
- Cancer de colon y recto Cancerología Citocromo P450 DNA Factor transcripción STAT3 Inmunohistoquímica Inflamación ARN interferencia Interleuquina 6 Micro ARN Metilación Anatomía patológica Cáncer Citoquina Enzima Aparato digestivo patología Intestino patología Colón patología Recto patología Silencio expresión genética Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04C Multiple tumors. Solid tumors. Tumors in childhood (general aspects)
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen Tumours
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 29094002
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/bjc.2014.540 
https://dx.doi.org/10.1038/bjc.2014.540
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