Synthesis of two distamycin analogues and their binding mode to d(CGCAAATTTGCG)2 in the 2:1 solution complexes as determined by two-dimensional 1H-NMR
- Author
- ANIMATI, F1 ; ARCAMONE, F. M1 ; CONTE, M. R2 ; FELICETTI, P1 ; GALEONE, A2 ; LOMBARDI, P1 ; MAYOL, L2 ; PALOMA, L. G2 ; ROSSI, C1
[1] Menarini ric. Sud, dip. chimica, 00040 Pomezia, Italy
[2] Univ. Napoli Federico II, dip. chimica sostanze naturali, 80131 Napoli, Italy - Source
Journal of medicinal chemistry (Print). 1995, Vol 38, Num 7, pp 1140-1149 ; ref : 28 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Affinité Amidine Anticancéreux Antiviral DNA Effet Overhauser Fixation biologique Interaction moléculaire Modèle moléculaire Modélisation Oligodésoxyribonucléotide Pyrrole dérivé Spectrométrie 2 dimensions Synthèse chimique Tétramère Distamycine Propionimidique acide3-[4-(4-[4-(4-carbamoyl-1-méthylpyrrole-2-carbonylamino)1-méthylpyrrole-2-carbonylamino]-1-méthylpyrrole-2-carbonylamino)-1-méthylpyrrole-2-carbonylamino] amide Propionimidique acide3-[4-(4-[4-(4-carbonylamino-1-méthylpyrrole-2-carbonylamino)1-méthylpyrrole-2-carbonylamino]-1-méthylpyrrole-2-carbonylamino)-1-méthylpyrrole-2-carbonylamino] amide Sillon mineur Stillamycine
- Keyword (en)
- Affinity Amidine Antineoplastic agent Antiviral DNA Overhauser effect Biological fixation Molecular interaction Molecular model Modeling Oligodeoxyribonucleotide Pyrrole derivatives Two dimension spectrometry Chemical synthesis Tetramer Minor groove
- Keyword (es)
- Afinidad Amidina Anticanceroso Antiviral DNA Efecto Overhauser Fijación biológica Interacción molecular Modelo molecular Modelización Oligodesoxirribonucleótido Pirrol derivado Espectrometría bidimensional Síntesis química Tetrámero
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S05 Antiviral agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3493112
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00007a011 
https://dx.doi.org/10.1021/jm00007a011
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