Synthesis and receptor binding of 5-amino[3H]2methyl-3-isothiazolol ([3H]thiomuscimol), a specific GABAA agonist photoaffinity label
- Author
- FRØLUND, B1 ; EBERT, B1 ; LAWRENCE, L. W; HURT, S. D; KROGSGAARD-LARSEN, P1
[1] Royal Danish school pharmacy, pharmabiotec res. cent., dep. medicinal chemistry, 2100 Copenhagen, Denmark - Source
Journal of labelled compounds & radiopharmaceuticals. 1995, Vol 36, Num 9, pp 877-889 ; ref : 17 ref
- ISSN
- 0362-4803
- Scientific domain
- Biochemistry, molecular biology, biophysics; Organic chemistry; Pharmacology drugs
- Publisher
- Wiley, Chichester
/
Wiley, New York, NY
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Agoniste Amine primaire Animal Cycle 5 chaînons Encéphale Hydrogène Isotope Hétérocycle soufre azote In vitro Marquage photoaffinité Marquage radioisotopique Rat Récepteur gabaergique A Synthèse chimique Système nerveux central Tritium Isothiazol-3-ol(5-aminométhyl) chlorhydrate Isothiazole-5-carboxylique acide(3-hydroxy) amide Isothiazole-5-carboxylique acide(3-éthoxy) ester méthyle Thiomuscimol Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Agonist Primary amine Animal Five membered ring Brain (vertebrata) Hydrogen Isotopes Sulfur nitrogen heterocycle In vitro Photoaffinity labelling Radiolabelling Rat Gabaergic receptor A Chemical synthesis Central nervous system Tritium Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Agonista Amina primaria Animal Ciclo 5 eslabones Encéfalo Hidrógeno Isótopo Heterociclo azufre nitrógeno In vitro Marcación fotoafinidad Marcación radioisotópica Rata Receptor gabaminérgico A Síntesis química Sistema nervioso central Tritio Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C06 Heterocyclic compounds / 001C03C06D Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms
- Discipline
- Organic chemistry
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 3622253
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1002/jlcr.2580360909 
https://dx.doi.org/10.1002/jlcr.2580360909
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