Synthesis and trazodone-like pharmacological profile of 1- and 2-[3-[4-(X)-1-piperazinyl]-propyl]-benzotriazoles
- Auteur
- CALIENDO, G1 ; DI CARLO, R; MELI, R; PERISSUTTI, E1 ; SANTAGADA, V1 ; SILIPO, C1 ; VITTORIA, A1
[1] Univ. Federico II, dip. chimica farmaceutica tossicologica, 80131 Naples, Italy - Source
European journal of medicinal chemistry. 1993, Vol 28, Num 12, pp 969-974 ; ref : 28 ref
- CODEN
- EJMCA5
- ISSN
- 0223-5234
- Domaine scientifique
- Organic chemistry; Pharmacology drugs
- Editeur
- Elsevier, Oxford
- Pays de publication
- United Kingdom
- Type de document
- Article
- Langue
- English
- Mot clé (fr)
- Alkylation Analgésique Antagoniste Antidépresseur Antihistaminique Composé aromatique Composé bicyclique Hétérocycle azote In vitro In vivo Pipérazine dérivé Relation structure activité Récepteur sérotoninergique Sympatholytique Benzotriazole(1-[3-pipérazinopropyl]) Benzotriazole(2-[3-pipérazinopropyl])
- Mot clé (en)
- Alkylation Analgesic Antagonist Antidepressant agent Antihistaminic Aromatic compound Bicyclic compound Nitrogen heterocycle In vitro In vivo Piperazine derivatives Structure activity relation Serotoninergic receptor Sympatholytic
- Mot clé (es)
- Alquilación Analgésico Antagonista Antidepresor Antihistamínico Compuesto aromático Compuesto bicíclico Heterociclo nitrógeno In vitro In vivo Relación estructura actividad Receptor serotoninérgico Simpaticolítico
- Classification
- Pascal
- 001 Sciences exactes et technologie / 001C Chimie / 001C03 Chimie organique / 001C03C Préparations et propriétés / 001C03C06 Composés hétérocycliques / 001C03C06C Cycles à plusieurs atomes n dans un même cycle, dans plusieurs cycles séparés et dans des cycles condensés
- Discipline
- Organic chemistry
- Provenance
- Inist-CNRS
- Base de données
- PASCAL
- Identifiant INIST
- 3829086
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/0223-5234(93)90053-H 
https://dx.doi.org/10.1016/0223-5234(93)90053-H
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