Structure-affinity relationship studies on 5-HT1A receptor ligands. II: Heterobicyclic phenylpiperazines with N4-aralkyl substituents
- Author
- VAN STEEN, B. J1 ; VAN WIJNGAARDEN, I1 ; TULP, M. T. M; SOUDIJN, W
[1] Solvay Duphar Research Laboratories, dep. medicinal chemistry, 1380 DA Weesp, Netherlands - Source
Journal of medicinal chemistry (Print). 1994, Vol 37, Num 17, pp 2761-2773 ; ref : 31 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Antidépresseur Befiperide Composé bicyclique Flesinoxan Hétérocycle Interaction moléculaire Ligand Modèle 3 dimensions Modélisation Pipérazine dérivé Relation structure activité Récepteur sérotoninergique S1A Tranquillisant Analyse comparative champ moléculaire Aralkylamine Modèle CoMFA Pipérazine(1-aryl) dérivé
- Keyword (en)
- Antidepressant agent Bicyclic compound Heterocyclic compound Molecular interaction Ligand Three dimensional model Modeling Piperazine derivatives Structure activity relation S1A receptor Tranquillizer Comparative molecular field analysis
- Keyword (es)
- Antidepresor Compuesto bicíclico Heterociclo Interacción molecular Ligando Modelo 3 dimensiones Modelización Relación estructura actividad Receptor serotoninérgico S1A Tranquilizante
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B09 Neurotransmitters. Neurotransmission. Receptors / 002B02B09C Serotoninergic system
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 4192903
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm00043a015 
https://dx.doi.org/10.1021/jm00043a015
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