A Toll-like receptor recognizes bacterial DNA
- Author
- HEMMI, Hiroaki1 2 ; TAKEUCHI, Osamu1 2 ; AKIRA, Shizuo1 2 ; KAWAI, Taro1 2 ; KAISHO, Tsuneyasu1 2 ; SATO, Shintaro1 2 ; SANJO, Hideki1 2 ; MATSUMOTO, Makoto1 2 ; HOSHINO, Katsuaki1 2 ; WAGNER, Hermann3 ; TAKEDA, Klyoshi1 2
[1] Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan
[2] Core Research for Evolutional Science and Technology, Japan Science and Technology Corporation, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan
[3] Institute of Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Trogerstr. 9, 81675 Munich, Germany - Source
Nature (London). 2000, Vol 408, Num 6813, pp 740-745 ; ref : 31 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Bactérie Cellule dendritique Cellule helper Cytokine DNA Immunité cellulaire Immunomodulation Immunostimulation Inflammation Lymphocyte T Macrophage Oligodésoxyribonucléotide Récepteur biologique Réponse immune Souris CpG Protéine TLR9 Mammalia Rodentia Vertebrata
- Keyword (en)
- Bacteria Dendritic cell Helper cell Cytokine DNA Cellular immunity Immunomodulation Immunostimulation Inflammation T-Lymphocyte Macrophage Oligodeoxyribonucleotide Biological receptor Immune response Mouse Mammalia Rodentia Vertebrata
- Keyword (es)
- Bacteria Célula dendrítica Célula auxiliar Citoquina DNA Inmunidad celular Inmunomodulación Inmunoestimulación Inflamación Linfocito T Macrófago Oligodesoxirribonucleótido Receptor biológico Respuesta inmune Ratón Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05B Bacteriology / 002A05B10 Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 830097
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
Access to the document
Install on your browser
DOI
10.1038/35047123 
https://dx.doi.org/10.1038/35047123
"O:13:\"PanistOpenUrl\":36:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000idc\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:16:\"10.1038\/35047123\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2000\";s:9:\"\u0000*\u0000volume\";s:3:\"408\";s:8:\"\u0000*\u0000issue\";s:4:\"6813\";s:8:\"\u0000*\u0000spage\";s:3:\"740\";s:8:\"\u0000*\u0000epage\";s:3:\"745\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"HEMMI\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:15:\"TAKEUCHI, Osamu\";i:1;s:13:\"AKIRA, Shizuo\";i:2;s:11:\"KAWAI, Taro\";i:3;s:17:\"KAISHO, Tsuneyasu\";i:4;s:14:\"SATO, Shintaro\";i:5;s:13:\"SANJO, Hideki\";i:6;s:17:\"MATSUMOTO, Makoto\";i:7;s:17:\"HOSHINO, Katsuaki\";i:8;s:15:\"WAGNER, Hermann\";i:9;s:15:\"TAKEDA, Klyoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Panist access
"O:12:\"IstexOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:16:\"10.1038\/35047123\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2000\";s:9:\"\u0000*\u0000volume\";s:3:\"408\";s:8:\"\u0000*\u0000issue\";s:4:\"6813\";s:8:\"\u0000*\u0000spage\";s:3:\"740\";s:8:\"\u0000*\u0000epage\";s:3:\"745\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"HEMMI\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:15:\"TAKEUCHI, Osamu\";i:1;s:13:\"AKIRA, Shizuo\";i:2;s:11:\"KAWAI, Taro\";i:3;s:17:\"KAISHO, Tsuneyasu\";i:4;s:14:\"SATO, Shintaro\";i:5;s:13:\"SANJO, Hideki\";i:6;s:17:\"MATSUMOTO, Makoto\";i:7;s:17:\"HOSHINO, Katsuaki\";i:8;s:15:\"WAGNER, Hermann\";i:9;s:15:\"TAKEDA, Klyoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Istex access
"O:16:\"UnpaywallOpenUrl\":35:{s:8:\"\u0000*\u0000email\";s:27:\"assistance-portail@inist.fr\";s:6:\"\u0000*\u0000fmt\";N;s:6:\"\u0000*\u0000doi\";s:16:\"10.1038\/35047123\";s:6:\"\u0000*\u0000pii\";N;s:7:\"\u0000*\u0000pmid\";N;s:9:\"\u0000*\u0000atitle\";N;s:9:\"\u0000*\u0000jtitle\";N;s:9:\"\u0000*\u0000stitle\";N;s:7:\"\u0000*\u0000date\";N;s:9:\"\u0000*\u0000volume\";N;s:8:\"\u0000*\u0000issue\";N;s:8:\"\u0000*\u0000spage\";N;s:8:\"\u0000*\u0000epage\";N;s:8:\"\u0000*\u0000pages\";N;s:7:\"\u0000*\u0000issn\";N;s:8:\"\u0000*\u0000eissn\";N;s:9:\"\u0000*\u0000aulast\";N;s:10:\"\u0000*\u0000aufirst\";N;s:9:\"\u0000*\u0000auinit\";N;s:10:\"\u0000*\u0000auinitm\";N;s:5:\"\u0000*\u0000au\";N;s:9:\"\u0000*\u0000aucorp\";N;s:7:\"\u0000*\u0000isbn\";N;s:8:\"\u0000*\u0000coden\";N;s:8:\"\u0000*\u0000genre\";N;s:7:\"\u0000*\u0000part\";N;s:9:\"\u0000*\u0000btitle\";N;s:8:\"\u0000*\u0000title\";N;s:8:\"\u0000*\u0000place\";N;s:6:\"\u0000*\u0000pub\";N;s:10:\"\u0000*\u0000edition\";N;s:9:\"\u0000*\u0000tpages\";N;s:9:\"\u0000*\u0000series\";N;s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";N;}"
Unpaywall access
"O:16:\"EuropePMCOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:16:\"10.1038\/35047123\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2000\";s:9:\"\u0000*\u0000volume\";s:3:\"408\";s:8:\"\u0000*\u0000issue\";s:4:\"6813\";s:8:\"\u0000*\u0000spage\";s:3:\"740\";s:8:\"\u0000*\u0000epage\";s:3:\"745\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"HEMMI\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:15:\"TAKEUCHI, Osamu\";i:1;s:13:\"AKIRA, Shizuo\";i:2;s:11:\"KAWAI, Taro\";i:3;s:17:\"KAISHO, Tsuneyasu\";i:4;s:14:\"SATO, Shintaro\";i:5;s:13:\"SANJO, Hideki\";i:6;s:17:\"MATSUMOTO, Makoto\";i:7;s:17:\"HOSHINO, Katsuaki\";i:8;s:15:\"WAGNER, Hermann\";i:9;s:15:\"TAKEDA, Klyoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Europe PubMed Central access
"O:11:\"BaseOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:16:\"10.1038\/35047123\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2000\";s:9:\"\u0000*\u0000volume\";s:3:\"408\";s:8:\"\u0000*\u0000issue\";s:4:\"6813\";s:8:\"\u0000*\u0000spage\";s:3:\"740\";s:8:\"\u0000*\u0000epage\";s:3:\"745\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"HEMMI\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:15:\"TAKEUCHI, Osamu\";i:1;s:13:\"AKIRA, Shizuo\";i:2;s:11:\"KAWAI, Taro\";i:3;s:17:\"KAISHO, Tsuneyasu\";i:4;s:14:\"SATO, Shintaro\";i:5;s:13:\"SANJO, Hideki\";i:6;s:17:\"MATSUMOTO, Makoto\";i:7;s:17:\"HOSHINO, Katsuaki\";i:8;s:15:\"WAGNER, Hermann\";i:9;s:15:\"TAKEDA, Klyoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
Base Search access
"O:12:\"ArXivOpenUrl\":35:{s:10:\"\u0000*\u0000openUrl\";N;s:6:\"\u0000*\u0000fmt\";s:7:\"journal\";s:6:\"\u0000*\u0000doi\";s:16:\"10.1038\/35047123\";s:6:\"\u0000*\u0000pii\";s:0:\"\";s:7:\"\u0000*\u0000pmid\";s:0:\"\";s:9:\"\u0000*\u0000atitle\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:9:\"\u0000*\u0000jtitle\";s:15:\"Nature (London)\";s:9:\"\u0000*\u0000stitle\";s:14:\"Nature (Lond.)\";s:7:\"\u0000*\u0000date\";s:4:\"2000\";s:9:\"\u0000*\u0000volume\";s:3:\"408\";s:8:\"\u0000*\u0000issue\";s:4:\"6813\";s:8:\"\u0000*\u0000spage\";s:3:\"740\";s:8:\"\u0000*\u0000epage\";s:3:\"745\";s:8:\"\u0000*\u0000pages\";s:0:\"\";s:7:\"\u0000*\u0000issn\";s:9:\"0028-0836\";s:8:\"\u0000*\u0000eissn\";s:0:\"\";s:9:\"\u0000*\u0000aulast\";s:5:\"HEMMI\";s:10:\"\u0000*\u0000aufirst\";s:7:\"Hiroaki\";s:9:\"\u0000*\u0000auinit\";s:0:\"\";s:10:\"\u0000*\u0000auinitm\";s:0:\"\";s:5:\"\u0000*\u0000au\";a:10:{i:0;s:15:\"TAKEUCHI, Osamu\";i:1;s:13:\"AKIRA, Shizuo\";i:2;s:11:\"KAWAI, Taro\";i:3;s:17:\"KAISHO, Tsuneyasu\";i:4;s:14:\"SATO, Shintaro\";i:5;s:13:\"SANJO, Hideki\";i:6;s:17:\"MATSUMOTO, Makoto\";i:7;s:17:\"HOSHINO, Katsuaki\";i:8;s:15:\"WAGNER, Hermann\";i:9;s:15:\"TAKEDA, Klyoshi\";}s:9:\"\u0000*\u0000aucorp\";s:0:\"\";s:7:\"\u0000*\u0000isbn\";s:0:\"\";s:8:\"\u0000*\u0000coden\";s:6:\"NATUAS\";s:8:\"\u0000*\u0000genre\";s:7:\"article\";s:7:\"\u0000*\u0000part\";s:0:\"\";s:9:\"\u0000*\u0000btitle\";s:0:\"\";s:8:\"\u0000*\u0000title\";s:45:\"A Toll-like receptor recognizes bacterial DNA\";s:8:\"\u0000*\u0000place\";s:6:\"London\";s:6:\"\u0000*\u0000pub\";s:17:\"Nature Publishing\";s:10:\"\u0000*\u0000edition\";s:0:\"\";s:9:\"\u0000*\u0000tpages\";s:0:\"\";s:9:\"\u0000*\u0000series\";s:0:\"\";s:8:\"\u0000*\u0000proxy\";s:30:\"http:\/\/proxyout.inist.fr:8080\/\";s:12:\"\u0000*\u0000integrite\";b:1;}"
arXiv access
