Induction of antigen-specific CD8 + T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine
- Author
- ROY, Michael J1 ; WU, Mary S1 ; WIDERA, Georg1 ; VESSEY, Rupert4 ; KING, Abbi5 ; OGG, Graham6 ; GALLIMORE, Awen6 ; HAYNES, Joel R1 ; FULLER, Deborah Heydenburg1 ; BARR, Lori James1 ; FULLER, James T1 ; TUSSEY, Lynda G2 ; SPELLER, Sue2 ; CULP, Jerilyn1 ; BURKHOLDER, Joseph K1 ; SWAIN, William F1 ; DIXON, Russell M3
[1] PowderJect Vaccines Inc., 585 Science Drive, Madison, WI 53711, United States
[2] GlaxoWellcome R&D, Virology Unit, Stevenage, SG1 2NY, United Kingdom
[3] Covance Clinical Research Unit, Madison, WI 53703, United States
[4] GlaxoWellcome R&D, Greenford, UB6 OHS, United Kingdom
[5] Human Immunology Unit, Institute of Moecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
[6] Nuffield Department of Medicine, John Radcliffe Hospital, Oxford, United Kingdom - Source
Vaccine. 2000, Vol 19, Num 7-8, pp 764-778 ; ref : 62 ref
- CODEN
- VACCDE
- ISSN
- 0264-410X
- Scientific domain
- Biotechnology; Immunology, immunopathology, allergology; Microbiology, infectious diseases; Virology
- Publisher
- Elsevier, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- DNA recombinant Enrobage Essai clinique Homme Hépatite virale B Immunité cellulaire Immunité humorale Immunogénicité Immunoprotection Or Particule métallique Système administration Vaccin génétique Virus hépatite B Voie intradermique Appareil digestif pathologie Foie pathologie Hepadnaviridae Infection Orthohepadnavirus Virose Virus
- Keyword (en)
- Recombinant DNA Coating Clinical trial Human Viral hepatitis B Cellular immunity Humoral immunity Immunogenicity Immunoprotection Gold Metal particle Delivery system Genetic vaccine Hepatitis B virus Intradermal administration Digestive diseases Hepatic disease Hepadnaviridae Infection Orthohepadnavirus Viral disease Virus
- Keyword (es)
- DNA recombinante Envoltura Ensayo clínico Hombre Hepatitis vírica B Inmunidad celular Inmunidad humoral Inmunogenicidad Inmunoprotección Oro Partícula metálica Sistema administración Vaccina genética Hepatitis B virus Vía intradérmica Aparato digestivo patología Hígado patología Hepadnaviridae Infección Orthohepadnavirus Virosis Virus
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B05 Infectious diseases / 002B05A General aspects / 002B05A02 Epidemiology. Vaccinations
- Discipline
- Infectious pathology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 840114
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0264-410X(00)00302-9 
https://dx.doi.org/10.1016/S0264-410X(00)00302-9
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