ICOS is essential for effective T-helper-cell responses
- Author
- TAFURI, Anna1 2 ; SHAHINIAN, Arda1 2 ; ODERMATT, Bernhard6 ; HO, Alexandra1 2 ; ITIE, Annick1 2 ; KORAN, Tom4 ; WHORISKEY, John S4 ; PAWSON, Tony3 ; PENNINGER, Josef M1 2 ; OHASHI, Pamela S2 ; MAK, Tak W1 2 ; BLADT, Friedheim3 ; YOSHINAGA, Steve K4 ; JORDANA, Manel5 ; WAKEHAM, Andrew1 2 ; BOUCHER, Louis-Martin1 2 ; BOUCHARD, Denls1 2 ; CHAN, Vera S. F2 ; DUNCAN, Gordon1 2
[1] Amgen Institute, 620 University Avenue, Toronto, Ontario M5G 2C1, Canada
[2] Ontario Cancer Institute, and Departments of Medical Biophysics and Immunology, University of Toronto, Toronto, Ontario M5G 2C1, Canada
[3] Mount Sinai Hospital, Samuel Lunenfeld Research Institute, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada
[4] Amgen, One Amgen Center Drive, Thousand Oaks, California 91320-1789, United States
[5] Department of Pathology and Molecular Medicine, Faculty of Health Science, McMaster University, Hamilton, Ontario L8N 3Z5, Canada
[6] University Hospital Zurich, Department of Pathology, 8091 Zurich, Switzerland - Source
Nature (London). 2001, Vol 409, Num 6816, pp 105-109 ; ref : 29 ref
- CODEN
- NATUAS
- ISSN
- 0028-0836
- Scientific domain
- Multidisciplinary
- Publisher
- Nature Publishing, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticorps Cellule helper Cytokine Immunité humorale Immunoglobuline Interaction cellulaire Lymphocyte B Lymphocyte T Récepteur biologique Réponse immune Souris Animal knockout Antigène CD40 Commutation isotype Costimulation Récepteur ICOS Mammalia Rodentia Vertebrata
- Keyword (en)
- Antibody Helper cell Cytokine Humoral immunity Immunoglobulins Cell cell interaction B-Lymphocyte T-Lymphocyte Biological receptor Immune response Mouse Knockout animal Isotype switching Costimulation ICOS receptor Mammalia Rodentia Vertebrata
- Keyword (es)
- Anticuerpo Célula auxiliar Citoquina Inmunidad humoral Inmunoglobulina Interacción celular Linfocito B Linfocito T Receptor biológico Respuesta inmune Ratón Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05C Virology / 002A05C03 Morphology, structure, chemical composition, physicochemical properties
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 859550
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/35051113 
https://dx.doi.org/10.1038/35051113
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