Differential selection of multidrug efflux mutants by trovafloxacin and ciprofloxacin in an experimental model of Pseudomonas aeruginosa acute pneumonia in rats
- Author
- JOIN-LAMBERT, O. F1 ; MICHEA-HAMZEHPOUR, M2 ; KÖHLER, T2 ; CHAU, F1 ; FAURISSON, F1 ; DAUTREY, S3 ; VISSUZAINE, C4 ; CARBON, C1 ; PECHERE, J.-C2
[1] INSERM EPI 9933, Hôpital Bichat-Claude Bernard, 75018 Paris, France
[2] Department of Genetics and Microbiology, CMU, 1 Rue Michel Servet, 1211 Geneva, Switzerland
[3] Service de Pharmacie Clinique et des Biomatériaux, Hôpital Bichat-Claude Bernard, 75018 Paris, France
[4] Service d' Anatomie-Pathologique, Hôpital Bichat-Claude Bernard, 75018 Paris, France - Source
Antimicrobial agents and chemotherapy. 2001, Vol 45, Num 2, pp 571-576 ; ref : 30 ref
- CODEN
- AACHAX
- ISSN
- 0066-4804
- Scientific domain
- Microbiology, infectious diseases; Pharmacology drugs
- Publisher
- American Society for Microbiology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Animal Antibactérien Appareil respiratoire Bactériose Chimiothérapie Ciprofloxacine Fluoroquinolone dérivé Mutation Pharmacocinétique Phénotype Plasma sanguin Pneumonie Poumon Pseudomonas aeruginosa Quinolone dérivé Rat Résistance Sang Sélection Traitement Transport biologique Trovafloxacine Voie intrapéritonéale Appareil respiratoire pathologie Bactérie Génétique Infection Mammalia Poumon pathologie Pseudomonadaceae Pseudomonadales Rodentia Vertebrata
- Keyword (en)
- Biological activity Animal Antibacterial agent Respiratory system Bacteriosis Chemotherapy Ciprofloxacin Fluoroquinolone derivatives Mutation Pharmacokinetics Phenotype Blood plasma Pneumonia Lung Pseudomonas aeruginosa Quinolone derivatives Rat Resistance Blood Selection Treatment Biological transport Trovafloxacin Intraperitoneal administration Respiratory disease Bacteria Genetics Infection Mammalia Lung disease Pseudomonadaceae Pseudomonadales Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Animal Antibacteriano Aparato respiratorio Bacteriosis Quimioterapia Ciprofloxacino Fluoroquinolone derivado Mutación Farmacocinética Fenotipo Plasma sanguíneo Neumonía Pulmón Pseudomonas aeruginosa Quinolone derivado Rata Resistencia Sangre Selección Tratamiento Transporte biológico Trovafloxacino Vía intraperitoneal Aparato respiratorio patología Bacteria Genética Infección Mammalia Pulmón patología Pseudomonadaceae Pseudomonadales Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A31 Biotechnology / 002A31C Methods. Procedures. Technologies / 002A31C02 Genetic technics / 002A31C02B Mutant screening / 002A31C02B1 Prokaryotes
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S02 Antibacterial agents
- Discipline
- Biotechnology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 912696
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1128/AAC.45.2.571-576.2001 
https://dx.doi.org/10.1128/AAC.45.2.571-576.2001
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