Effects of chemically modified tetracyclines (CMTs) in sensitive, multidrug resistant and apoptosis resistant leukaemia cell lines
- Author
- TOLOMEO, Manlio1 ; GRIMAUDO, Stefania1 ; MILANO, Salvatore2 ; ROSA, Marzia La2 ; FERLAZZO, Viviana2 ; DI BELLA, Gloria2 ; BARBERA, Caterina3 ; SIMONI, Daniele4 ; D'AGOSTINO, Pietro5 ; CILLARI, Enrico3
[1] Divisione di Ematologia e Servizio AIDS, Policlinico Universitario Paolo Giaccone, via del Vespro 129, 90127 Palermo, Italy
[2] Dipartimento di Biopatologia e Metodologie Biomediche, Facolta'di Medicina, Universita'di Palermo, Corso Tukory 211, 90134 Palermo, Italy
[3] Laboratorio di Patologia Clinica e Microbiologia, Azienda Ospedaliera V Cervello, via Trabucco 180, 90146 Palermo, Italy
[4] Dipartimento di Scienze Farmaceutiche, Facolta'di Farmacia, Universita'di Ferrara, largo Fossato di Mortara 17/19, 44100 Ferrara, Italy
[5] Servizio di Immunoematologia, Policlinico Universitario Paolo Giaccone, via del Vespro 129, 90127 Palermo, Italy - Source
British journal of pharmacology. 2001, Vol 133, Num 2, pp 306-314 ; ref : 1 p.1/4
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Antibactérien Anticancéreux Apoptose Cellule tumorale Cysteine endopeptidases Cytotoxicité In vitro Lignée cellulaire établie Mort cellulaire Multiplication cellulaire Mécanisme action Relation structure activité Résistance multiple Test sensibilité médicamenteuse Tétracycline dérivé Tétracycline Caspase Lignée HL60 Enzyme Hydrolases Peptidases
- Keyword (en)
- Biological activity Antibacterial agent Antineoplastic agent Apoptosis Tumor cell Cysteine endopeptidases Cytotoxicity In vitro Established cell line Cell death Cell proliferation Mechanism of action Structure activity relation Multiple resistance Drug susceptibility test Tetracycline derivatives Tetracycline Enzyme Hydrolases Peptidases
- Keyword (es)
- Actividad biológica Antibacteriano Anticanceroso Apoptosis Célula tumoral Cysteine endopeptidases Citotoxicidad In vitro Línea celular establecida Muerte celular Multiplicación celular Mecanismo acción Relación estructura actividad Resistencia múltiple Prueba sensibilidad medicamentosa Tetraciclina derivado Tetraciclina Enzima Hydrolases Peptidases
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 998906
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjp.0704068 
https://dx.doi.org/10.1038/sj.bjp.0704068
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