Pharmacokinetic/Pharmacodynamic (PK/PD) Indices of Antibiotics Predicted by a Semimechanistic PKPD Model: a Step toward Model-Based Dose OptimizationNIELSEN, Elisabet I; CARS, Otto; FRIBERG, Lena E et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 10, pp 4619-4630, issn 0066-4804, 12 p.Article

The shape of the myelosuppression time profile is related to the probability of developing neutropenic fever in patients with docetaxel-induced grade IV neutropeniaHANSSON, Emma K; FRIBERG, Lena E.Cancer chemotherapy and pharmacology. 2012, Vol 69, Num 4, pp 881-890, issn 0344-5704, 10 p.Article

Predicting In Vitro Antibacterial Efficacy across Experimental Designs with a Semimechanistic Pharmacokinetic-Pharmacodynamic ModelNIELSEN, Elisabet I; CARS, Otto; FRIBERG, Lena E et al.Antimicrobial agents and chemotherapy. 2011, Vol 55, Num 4, pp 1571-1579, issn 0066-4804, 9 p.Article

Integrated Population Pharmacokinetic Analysis of Voriconazole in Children, Adolescents, and AdultsFRIBERG, Lena E; RAVVA, Patanjali; KARLSSON, Mats O et al.Antimicrobial agents and chemotherapy. 2012, Vol 56, Num 6, pp 3032-3042, issn 0066-4804, 11 p.Article

Application of pharmacokinetic-pharmacodynamic modelling in management of QT abnormalities after citalopram overdoseISBISTER, Geoffrey K; FRIBERG, Lena E; DUFFULL, Stephen B et al.Intensive care medicine (Print). 2006, Vol 32, Num 7, pp 1060-1065, issn 0342-4642, 6 p.Article

Pharmacokinetic-pharmacodynamic modelling of QT interval prolongation following citalopram overdosesFRIBERG, Lena E; ISBISTER, Geoffrey K; DUFFULL, Stephen B et al.British journal of clinical pharmacology. 2006, Vol 61, Num 2, pp 177-190, issn 0306-5251, 14 p.Article

Comparison of the agonist-antagonist interaction model and the pool model for the effect of remoxipride on prolactinGUANGLI MA; FRIBERG, Lena E; MOVIN-OSSWAID, Gunilia et al.British journal of clinical pharmacology. 2010, Vol 70, Num 6, pp 815-824, issn 0306-5251, 10 p.Article

Model of chemotherapy-induced myelosuppression with parameter consistency across drugsFRIBERG, Lena E; HENNINGSSON, Anja; MAAS, Hugo et al.Journal of clinical oncology. 2002, Vol 20, Num 24, pp 4713-4721, issn 0732-183X, 9 p.Article

Pharmacokinetic-pharmacodynamic modelling of the schedule-dependent effect of the anti-cancer agent CHS 828 in a rat hollow fibre modelFRIBERG, Lena E; HASSAN, Saadia B; LINDHAGEN, Elin et al.European journal of pharmaceutical sciences. 2005, Vol 25, Num 1, pp 163-173, issn 0928-0987, 11 p.Article

Pharmacokinetic-Pharmacodynamic Model for Gentamicin and Its Adaptive Resistance with Predictions of Dosing Schedules in Newborn InfantsMOHAMED, Ami F; NIELSEN, Elisabet I; CARS, Otto et al.Antimicrobial agents and chemotherapy. 2012, Vol 56, Num 1, pp 179-188, issn 0066-4804, 10 p.Article

Influence of Cremophor EL and Genetic Polymorphisms on the Pharmacokinetics of Paclitaxel and Its Metabolites Using a Mechanism-Based ModelFRANSSON, Martin N; GREEN, Henrik; LITTON, Jan-Eric et al.Drug metabolism and disposition. 2011, Vol 39, Num 2, pp 247-255, issn 0090-9556, 9 p.Article

Developmental Pharmacokinetics of Gentamicin in Preterm and Term Neonates Population Modelling of a Prospective StudyNIELSEN, Elisabet I; SANDSTRÖM, Marie; HARTVIG HONORE, Per et al.Clinical pharmacokinetics. 2009, Vol 48, Num 4, pp 253-263, issn 0312-5963, 11 p.Article

The population pharmacokinetics of citalopram after deliberate self-poisoning : A bayesian approachFRIBERG, Lena E; ISBISTER, Geoffrey K; HACKETT, L. Peter et al.Journal of pharmacokinetics and pharmacodynamics (Print). 2005, Vol 32, Num 3-4, pp 571-605, issn 1567-567X, 35 p.Article

Pharmacodynamic differences between species exemplified by the novel anticancer agent CHS 828LINDHAGEN, Elin; VIG HJARNAA, Pernille-Julia; FRIBERG, Lena E et al.Drug development research. 2004, Vol 61, Num 4, pp 218-226, issn 0272-4391, 9 p.Article

Population Pharmacokinetics of Tacrolimus in Pediatric Hematopoietic Stem Cell Transplant Recipients: New Initial Dosage Suggestions and a Model-Based Dosage Adjustment ToolWALLIN, Johan E; FRIBERG, Lena E; FASTH, Anders et al.Therapeutic drug monitoring. 2009, Vol 31, Num 4, pp 457-466, issn 0163-4356, 10 p.Article

Mechanistic models for myelosuppressionFRIBERG, Lena E; KARLSSON, Mats O.Investigational new drugs. 2003, Vol 21, Num 2, pp 183-194, issn 0167-6997, 12 p.Article

Dose response of whole-grain biomarkers : alkylresorcinols in human plasma and their metabolites in urine in relation to intakeLANDBERG, Rikard; AMAN, Per; FRIBERG, Lena E et al.The American journal of clinical nutrition. 2009, Vol 89, Num 1, pp 290-296, issn 0002-9165, 7 p.Article

Quantitative analysis of colistin A and colistin B in plasma and culture medium using a simple precipitation step followed by LC/MS/MSJANSSON, Britt; KARVANEN, Matti; CARS, Otto et al.Journal of pharmaceutical and biomedical analysis. 2009, Vol 49, Num 3, pp 760-767, issn 0731-7085, 8 p.Article

Influence of Polymorphic OATP1 B-Type Carriers on the Disposition of DocetaxelDE GRAAN, Anne-Joy M; LANCASTER, Cynthia S; CORYDON, Thomas J et al.Clinical cancer research (Print). 2012, Vol 18, Num 16, pp 4433-4440, issn 1078-0432, 8 p.Article

Influence of Smoking on the Pharmacokinetics and Toxicity Profiles of Taxane TherapyDE GRAAN, Anne-Joy M; LOOS, Walter J; FRIBERG, Lena E et al.Clinical cancer research (Print). 2012, Vol 18, Num 16, pp 4425-4432, issn 1078-0432, 8 p.Article

Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamicsSTEIMER, Jean-Louis; DAHL, Svein G; FRIBERG, Lena E et al.European journal of cancer (1990). 2010, Vol 46, Num 1, pp 21-32, issn 0959-8049, 12 p.Article

Population pharmacokinetics of itraconazole and its active metabolite hydroxy-itraconazole in paediatric cystic fibrosis and bone marrow transplant patientsHENNIG, Stefanie; WAINWRIGHT, Claire E; BELL, Scott C et al.Clinical pharmacokinetics. 2006, Vol 45, Num 11, pp 1099-1114, issn 0312-5963, 16 p.Article

A population pharmacokinetic/pharmacodynamic model of thrombocytopenia characterizing the effect of trastuzumab emtansine (T-DM1) on platelet counts in patients with HER2-positive metastatic breast cancerBENDER, Brendan C; SCHAEDELI-STARK, Franziska; KOCH, Reinhold et al.Cancer chemotherapy and pharmacology. 2012, Vol 70, Num 4, pp 591-601, issn 0344-5704, 11 p.Article

Cigarette smoking and irinotecan treatment : Pharmacokinetic interaction and effects on neutropeniaVAN DER BOL, Jessica M; MATHIJSSEN, Ron H. J; LOOS, Walter J et al.Journal of clinical oncology. 2007, Vol 25, Num 19, pp 2719-2726, issn 0732-183X, 8 p.Article

Model-Based Neutrophil-Guided Dose Adaptation in Chemotherapy: Evaluation of Predicted Outcome with Different Types and Amounts of InformationWALLIN, Johan E; FRIBERG, Lena E; KARLSSON, Mats O et al.Basic & clinical pharmacology & toxicology (Print). 2010, Vol 106, Num 3, pp 234-242, issn 1742-7835, 9 p.Conference Paper