Stimulation of inflammatory responses in vitro and in vivo by lipophilic HMG-CoA reductase inhibitors
- Author
- KIENER, Peter A1 ; DAVIS, Patricia M1 ; MURRAY, Judy L1 ; YOUSSEF, Sonia2 ; RANKIN, Bruce M1 ; KOWALA, Mark2
[1] Department of Immunology and Inflammation, K14-09, Bristol-Myers Squibb, PRI, PO Box 4000, Princeton, NJ 08543, United States
[2] Department of Cardiocascular Drug Discovery, Bristol-Myers Squibb, PRI, Princeton, NJ 08543, United States - Source
International immunopharmacology. 2001, Vol 1, Num 1, pp 105-118 ; ref : 55 ref
- ISSN
- 1567-5769
- Scientific domain
- Immunology, immunopathology, allergology; Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Animal Atorvastatine Cavité péritonéale Cytokine Facteur nécrose tumorale α Hydroxymethylglutaryl-CoA reductase Immunomodulation Immunostimulation In vitro In vivo Inflammation Inhibiteur enzyme Interleukine 1β Interleukine 8 Leucocyte Lignée cellulaire établie Lipophilie Monocyte Pravastatine Réponse immune Simvastatine Souris Traitement Voie orale Statine Enzyme Mammalia Oxidoreductases Rodentia Vertebrata
- Keyword (en)
- Biological activity Animal Atorvastatin Peritoneal cavity Cytokine Tumor necrosis factor α Hydroxymethylglutaryl-CoA reductase Immunomodulation Immunostimulation In vitro In vivo Inflammation Enzyme inhibitor Interleukin 1β Interleukin 8 Leukocyte Established cell line Lipophily Monocyte Pravastatin Immune response Simvastatin Mouse Treatment Oral administration Enzyme Mammalia Oxidoreductases Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Animal Atorvastatina Cavidad peritoneal Citoquina Factor necrosis tumoral α Hydroxymethylglutaryl-CoA reductase Inmunomodulación Inmunoestimulación In vitro In vivo Inflamación Inhibidor enzima Interleuquina 1β Interleuquina 8 Leucocito Línea celular establecida Lipofilia Monocito Pravastatina Respuesta inmune Simvastatina Ratón Tratamiento Vía oral Enzima Mammalia Oxidoreductases Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02Q Immunomodulators
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1011713
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0162-3109(00)00272-1 
https://dx.doi.org/10.1016/S0162-3109(00)00272-1
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