Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
- Author
- SPITTAELS, K1 ; VAN DEN HAUTE, C1 ; LOOS, R4 ; VAN LEUVEN, F1 ; VAN DORPE, J1 ; BRUYNSEELS, K1 ; VANDEZANDE, K1 ; LAENEN, I1 ; GEERTS, H2 ; MERCKEN, M2 ; SCIOT, R3 ; VAN LOMMEL, A3
[1] Experimental Genetics Group, Center for Human Genetics, Flemish Institute for Biotechnology, Katholieke Universiteit Leuven, Leuven, Belgium
[2] Janssen Research Foundation, Beerse, Belgium
[3] Department of Pathology, University Hospitals Leuven, Leuven, Belgium
[4] Department of Genetic Epidemiology, Katholieke Universiteit Leuven, Leuven, Belgium - Source
The American journal of pathology. 1999, Vol 155, Num 6, pp 2153-2165 ; ref : 68 ref
- CODEN
- AJPAA4
- ISSN
- 0002-9440
- Scientific domain
- Medical oncology; Medical laboratory techniques; General medicine general surgery
- Publisher
- American Society for Investigative Pathology, Bethesda, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Analyse quantitative Animal transgénique Animal Axone Démence Encéphale Immunohistochimie Microscopie électronique Modèle animal Moelle épinière Méthode immunoblotting Parkinson maladie Protéine tau Souris Surexpression génique Démence frontotemporale Anatomopathologie Biologie moléculaire Encéphale pathologie Extrapyramidal syndrome Maladie dégénérative Mammalia Rodentia Système nerveux central pathologie Système nerveux pathologie Vertebrata
- Keyword (en)
- Quantitative analysis Transgenic animal Animal Axon Dementia Brain (vertebrata) Immunohistochemistry Electron microscopy Animal model Spinal cord Immunoblotting assay Parkinson disease Tau protein Mouse Gene overexpression Pathology Molecular biology Cerebral disorder Extrapyramidal syndrome Degenerative disease Mammalia Rodentia Central nervous system disease Nervous system diseases Vertebrata
- Keyword (es)
- Análisis cuantitativo Animal transgénico Animal Axón Demencia Encéfalo Inmunohistoquímica Microscopía electrónica Modelo animal Médula espinal Parkinson enfermedad Proteína tau Ratón Sobreexpressión genética Anatomía patológica Biología molecular Encéfalo patología Extrapiramidal síndrome Enfermedad degenerativa Mammalia Rodentia Sistema nervosio central patología Sistema nervioso patología Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1206444
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0002-9440(10)65533-2 
https://dx.doi.org/10.1016/S0002-9440(10)65533-2
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