Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice

Author

VAN OOSTROM, C. T. M¹ ; BOEVE, M¹ ; VAN DEN BERG, J¹ ; DE VRIES, A¹ ; DOLLE, M. E. T² ; BEEMS, R. B¹ ; VAN KREIJL, C. F¹ ; VIJG, J² ; VAN STEEG, H¹
[1] National Institute of Public Health and the Environment (RIVM), Laboratory of Health Effects Research, Department of Carcinogenesis, Mutagenesis and Genetics, Bilthoven, Netherlands
[2] Institute for Drug Development (CTRC) and University of Texas Health Science Center, San Antonio, Texas, United States

Issue title

Transgenics

Author (monograph)

HEDDLE, John A (Editor)¹ ; GLICKMAN, Barry W (Editor)² ; NOHMI, Takehiko (Editor)³ ; VAN STEEG, Harry (Editor)⁴
[1] York University, Toronto, Ontario, M3J 1P3, Canada
[2] University of Victoria, Victoria, British Columbia, V8L 3S1, Canada
[3] National Institute of Health Sciences, Tokyo 158, Japan
[4] National Institute of Public Health and the Environment (RIVM), PO Box 1, Bilthoven, Netherlands

Source

Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 124-130 ; ref : 24 ref

CODEN

EMMUEG

ISSN

0893-6692

Scientific domain

Biochemistry, molecular biology, biophysics; Environment; Genetics

Publisher

Wiley-Liss, New York, NY

Publication country

United States

Document type

Article

Language

English

Keyword (fr)

Animal transgénique Benzo[a]pyrène Carcinogenèse DNA Gène TP53 Modèle animal Mutation Perte hétérozygotie Réparation Souris Test carcinogénicité Test mutagénicité Toxicité Tumeur Gène lacZ Carcinogène Composé aromatique polycyclique Gène suppresseur tumeur Mammalia Rodentia Vertebrata

Keyword (en)

Transgenic animal Carcinogenesis DNA TP53 Gene Animal model Mutation Loss of heterozygosity Repair Mouse Carcinogenicity testing Mutagenicity testing Toxicity Tumor Carcinogen Polycyclic aromatic compound Tumor suppressor gene Mammalia Rodentia Vertebrata

Keyword (es)

Animal transgénico Carcinogénesis DNA Gen TP53 Modelo animal Mutación Pérdida heterozigosis Reparación Ratón Prueba carcinogenicidad Prueba mutagenicidad Toxicidad Tumor Carcinógeno Compuesto aromático policíclico Gen supresor tumor Mammalia Rodentia Vertebrata

Classification

Pascal

002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04H Cell physiology / 002A04H04 Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes

Discipline

Molecular and cell biology

Origin

Inist-CNRS

Database

PASCAL

INIST identifier

1210959

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS