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Detection of cyclophosphamide-induced mutations at the Hprt but not the lacI locus in splenic lymphocytes of exposed mice

Author
WALKER, V. E1 2 ; ANDREWS, J. L3 ; UPTON, P. B1 ; SKOPEK, T. R1 ; DEBOER, J. G4 ; WALKER, D. M2 ; XIAOCHU SHI2 ; SUSSMAN, H. E2 ; GORELICK, N. J3
[1] Department of Pathology and Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina, United States
[2] Wadsworth Center, New York State Department of Health, Albany, New York, United States
[3] The Procter and Gamble Company, Miami Valley Laboratories, Cincinnati, Ohio, United States
[4] Biology Department, Center for Environmental Health, University of Victoria, British Columbia, Canada
Issue title
Transgenics
Author (monograph)
HEDDLE, John A (Editor)1 ; GLICKMAN, Barry W (Editor)2 ; NOHMI, Takehiko (Editor)3 ; VAN STEEG, Harry (Editor)4
[1] York University, Toronto, Ontario, M3J 1P3, Canada
[2] University of Victoria, Victoria, British Columbia, V8L 3S1, Canada
[3] National Institute of Health Sciences, Tokyo 158, Japan
[4] National Institute of Public Health and the Environment (RIVM), PO Box 1, Bilthoven, Netherlands
Source

Environmental and molecular mutagenesis (Print). 1999, Vol 34, Num 2-3, pp 167-181 ; ref : 1 p.1/4

CODEN
EMMUEG
ISSN
0893-6692
Scientific domain
Biochemistry, molecular biology, biophysics; Environment; Genetics
Publisher
Wiley-Liss, New York, NY
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Animal transgénique Cyclophosphamide Hypoxanthine phosphoribosyltransferase In vivo Lymphocyte Mutation Souris Test mutagénicité Toxicité Gène lacI Agent alkylant Anticancéreux Enzyme Glycosyltransferases Mammalia Modèle animal Moutarde à l'azote Pentosyltransferases Rodentia Transferases Vertebrata
Keyword (en)
Transgenic animal Cyclophosphamide Hypoxanthine phosphoribosyltransferase In vivo Lymphocyte Mutation Mouse Mutagenicity testing Toxicity Alkylating agent Antineoplastic agent Enzyme Glycosyltransferases Mammalia Animal model Nitrogen mustard Pentosyltransferases Rodentia Transferases Vertebrata
Keyword (es)
Animal transgénico Ciclofosfamida Hypoxanthine phosphoribosyltransferase In vivo Linfocito Mutación Ratón Prueba mutagenicidad Toxicidad Agente alquilante Anticanceroso Enzima Glycosyltransferases Mammalia Modelo animal Mostaza al nitrógeno Pentosyltransferases Rodentia Transferases Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03N Chemical mutagenesis

Discipline
Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1211056

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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