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Antitumor agents. Part 209: Pheophorbide-a derivatives as photo-independent cytotoxic agents

Author
WONGSINKONGMAN, Prapai1 ; BROSSI, Arnold1 ; WANG, Hui-Kang1 ; BASTOW, Kenneth F1 ; LEE, Kuo-Hsiung1
[1] Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7360, United States
Source

Bioorganic & medicinal chemistry. 2002, Vol 10, Num 3, pp 583-591

ISSN
0968-0896
Scientific domain
Biochemistry, molecular biology, biophysics; Pharmacology drugs
Publisher
Elsevier Science, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Anticancéreux Cassure bicaténaire Composé polycyclique Coordinat organique Cytotoxicité DNA Homme Hétérocycle azote In vitro Isolement Lignée cellulaire Macrocycle Origine végétale Photosensibilisant Porphyrine métallique Relation structure activité Synthèse chimique Tumeur maligne Zinc Complexe Chlorine e6 ester triméthyle Garuga pinnata Phéophorbide a(132-hydroxy) ester méthyle Angiospermae Burseraceae Dicotyledones Spermatophyta
Keyword (en)
Antineoplastic agent Double strand break Polycyclic compound Organic ligand Cytotoxicity DNA Human Nitrogen heterocycle In vitro Isolation Cell line Macrocycle Plant origin Photosensitizer Metalloporphyrin Structure activity relation Chemical synthesis Malignant tumor Zinc Complexes Angiospermae Burseraceae Dicotyledones Spermatophyta
Keyword (es)
Anticanceroso Ruptura bicatenaria Compuesto policíclico Ligando orgánico Citotoxicidad DNA Hombre Heterociclo nitrógeno In vitro Aislamiento Línea celular Macrociclo Origen vegetal Fotosensibilizante Porfirina metálica Relación estructura actividad Síntesis química Tumor maligno Zinc Complejo Angiospermae Burseraceae Dicotyledones Spermatophyta
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B04 Tumors / 002B04H Treatment. General aspects / 002B04H02 Treatment with physical agents / 002B04H02B Photoradiation therapy and photosensitizing agent

Discipline
Pharmacological treatments Tumours
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
13427733

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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