The coffee components kahweol and cafestol induce γ-glutamylcysteine synthetase, the rate limiting enzyme of chemoprotective glutathione synthesis, in several organs of the rat
- Author
- HUBER, Wolfgang W1 ; SCHARF, Gerlinde1 ; ROSSMANITH, Walter1 ; PRUSTOMERSKY, Sonja1 ; GRASL-KRAUPP, Bettina1 ; PETER, Barbara1 ; TURESKY, Robert J2 ; SCHULTE-HERMANN, Rolf1
[1] Institut für Krebsforschung, University of Vienna, Borschkegasse 8A, 1090 Vienna, Austria
[2] Nestlé Research Center, Vers-chez-les-Blanc, 1000 Lausanne, Switzerland - Source
Archives of toxicology. 2002, Vol 75, Num 11-12, pp 685-694 ; ref : 1 p.3/4
- CODEN
- ARTODN
- ISSN
- 0340-5761
- Scientific domain
- Toxicology
- Publisher
- Springer, Berlin
- Publication country
- Germany
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Aliment Animal Antimutagène Café Côlon Diterpène Foie Glutamate-cysteine ligase Glutathion Mécanisme action Origine végétale Poumon Prévention Rat Rein Spécificité organe Voie orale Cafestol Kahwéol Carbon-nitrogen ligases Enzyme Ligases Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Food Animal Antimutagen Coffee Colon Diterpene Liver Glutamate-cysteine ligase Glutathione Mechanism of action Plant origin Lung Prevention Rat Kidney Organ specificity Oral administration Carbon-nitrogen ligases Enzyme Ligases Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Alimento Animal Antimutágeno Café Colón Diterpeno Hígado Glutamate-cysteine ligase Glutatión Mecanismo acción Origen vegetal Pulmón Prevención Rata Riñón Especificidad órgano Vía oral Carbon-nitrogen ligases Enzima Ligases Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B03 Toxicology / 002B03N Chemical mutagenesis
- Discipline
- Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13465174
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1007/s00204-001-0295-5 
https://dx.doi.org/10.1007/s00204-001-0295-5
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