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The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells

Author
HEROLD, Christoph1 ; GANSLMAYER, Marion1 ; OCKER, Matthias1 ; HERMANN, Martin2 ; GEERTS, Albert3 ; HAHN, Eckhart G1 ; SCHUPPAN, Detlef1
[1] Department of Medicine I, University of Erlangen-Nuernberg, Krankenhausstrasse 12, 91054 Erlangen, Germany
[2] Department of Medicine III, University of Erlangen-Nuernberg, Krankenhausstrasse 12, 91054 Erlangen, Germany
[3] Department of Medical Cell Biology, University of Newcastle, Newcastle upon Tyne, United Kingdom
Source

Journal of hepatology. 2002, Vol 36, Num 2, pp 233-240 ; ref : 37 ref

CODEN
JOHEEC
ISSN
0168-8278
Scientific domain
Gastroenterology
Publisher
Elsevier, Oxford
Publication country
United Kingdom
Document type
Article
Language
English
Keyword (fr)
Activité biologique Apoptose Carcinome hépatocellulaire Chimiothérapie Culture cellulaire Etude expérimentale Homme Inhibiteur enzyme Multiplication cellulaire Trichostatine A Appareil digestif pathologie Biologie cellulaire Foie pathologie Tumeur maligne
Keyword (en)
Biological activity Apoptosis Hepatocellular carcinoma Chemotherapy Cell culture Experimental study Human Enzyme inhibitor Cell proliferation Digestive diseases Cell biology Hepatic disease Malignant tumor
Keyword (es)
Actividad biológica Apoptosis Carcinoma hepatocelular Quimioterapia Cultivo celular Estudio experimental Hombre Inhibidor enzima Multiplicación celular Aparato digestivo patología Biología celular Hígado patología Tumor maligno
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
13486444

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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