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Use of an immobilised human serum albumin HPLC column as a probe of drug-protein interactions: the reversible binding of valproate

Author
BERTUCCI, C1 ; ANDRISANO, V1 ; GOTTI, R1 ; CAVRINI, V1
[1] Dipartimento di Scienze Farmaceutiche, Università di Bologna, via Belmeloro 6, 40126-Bologna, Italy
Issue title
Analysis of bioaffinity using separation systems
Author (monograph)
SHIBUKAWA, Akimasa (Editor)1
[1] Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan
Source

Journal of chromatography. B, Biomedical sciences and applications. 2002, Vol 768, Num 1, pp 147-155 ; ref : 29 ref

ISSN
1387-2273
Scientific domain
Biochemistry, molecular biology, biophysics; Medical laboratory techniques
Publisher
Elsevier Science, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Keyword (fr)
Anticonvulsivant Bilirubine Chromatographie HPLC Enantiomère Fixation biologique Homme Interaction moléculaire Médicament Méthode analyse Méthode séparation Pharmacocinétique Protéine liaison Site fixation Sérumalbumine Valproate semisodique
Keyword (en)
Anticonvulsant Bilirubin HPLC chromatography Enantiomer Biological fixation Human Molecular interaction Drug Analysis method Separation method Pharmacokinetics Binding protein Binding site Serum albumin Valproate semisodium
Keyword (es)
Anticonvulsivante Bilirrubina Cromatografía HPLC Enantiómero Fijación biológica Hombre Interacción molecular Medicamento Método análisis Método separación Farmacocinética Proteína enlace Sitio fijación Seroalbúmina Valproato semisódico
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions

Discipline
General pharmacology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
13489257

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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