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Improvement of the physicochemical and biopharmaceutical properties of insulin by poly(ethylene glycol) conjugation

Author
CALICETI, P1 ; VERONESE, F. M1
[1] Department of Pharmaceutical Sciences, University of Padua, Via F. Marzolo 5, 35131 Padova, Italy
Issue title
Conjugates: Towards Molecular Pharmaceutics
Source

STP pharma sciences. 1999, Vol 9, Num 1, pp 107-113 ; ref : 35 ref

ISSN
1157-1489
Scientific domain
Pharmacology drugs
Publisher
Editions de santé, Paris
Publication country
France
Document type
Article
Language
English
Keyword (fr)
Activité biologique Animal Composé conjugué Dégradation enzymatique Ethylène oxyde polymère Forme pharmaceutique Glucose Hormone pancréatique Hormone protéine Hypoglycémiant Insuline Pharmacocinétique Plasma sanguin Polymère vecteur Propriété physicochimique Rat Stabilité Technologie pharmaceutique Vecteur médicament Voie intraveineuse Voie souscutanée Mammalia Rodentia Vertebrata
Keyword (en)
Biological activity Animal Conjugated compound Enzymatic digestion Ethylene oxide polymer Dosage form Glucose Pancreatic hormone Protein hormone Hypoglycemic agent Insulin Pharmacokinetics Blood plasma Control release polymer Physicochemical properties Rat Stability Pharmaceutical technology Drug carrier Intravenous administration Subcutaneous administration Mammalia Rodentia Vertebrata
Keyword (es)
Actividad biológica Animal Compuesto conjugado Degradación enzimática Etileno óxido polímero Forma farmacéutica Glucosa Hormona pancreática Hormona proteina Hipoglicemiante Insulina Farmacocinética Plasma sanguíneo Polímero vector Propiedad fisicoquímica Rata Estabilidad Tecnología farmacéutica Vector medicamento Vía intravenosa Vía subcutánea Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry

Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02O Hormones. Endocrine system

Discipline
General pharmacology Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
1351219

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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