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Stereodefined synthesis of O3'-labeled uracil nucleosides. 3'-[17O]-2'-azido-2'-deoxyuridine 5'-diphosphate as a probe for the mechanism of inactivation of ribonucleotide reductases

Author
WNUK, Stanislaw F1 ; CHOWDHURY, Saiful M1 ; GARCIA, Pedro I1 ; ROBINS, Morris J2
[1] Department of Chemistry, Florida International University, Miami, Florida 33199, United States
[2] Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602, United States
Source

Journal of organic chemistry. 2002, Vol 67, Num 6, pp 1816-1819

CODEN
JOCEAH
ISSN
0022-3263
Scientific domain
Biochemistry, molecular biology, biophysics; Organic chemistry
Publisher
American Chemical Society, Washington, DC
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Activité biologique Azide Composé marqué Cyclonucléoside Désoxyuridine Inactivation Nucléoside Oxygène 17 Ribonucleoside-diphosphate reductase Synthèse chimique Uracile nucléotide Uridine(2'-azido-2'-désoxy)-5'-diphosphate Uridine(2,3'-anhydro) Enzyme Oxidoreductases
Keyword (en)
Biological activity Organic azide Labelled compound Cyclonucleoside Deoxyuridine Inactivation Nucleoside Oxygen 17 Ribonucleoside-diphosphate reductase Chemical synthesis Uracil nucleotide Enzyme Oxidoreductases
Keyword (es)
Actividad biológica Azida orgánica Compuesto marcado Ciclonucleósido Inactivación Nucleósido Ribonucleoside-diphosphate reductase Síntesis química Uracilo nucleótido Enzima Oxidoreductases
Classification
Pascal
001 Exact sciences and technology / 001C Chemistry / 001C03 Organic chemistry / 001C03C Preparations and properties / 001C03C07 Carbohydrates. Nucleosides and nucleotides / 001C03C07B Nucleosides, nucleotides and oligonucleotides

Pascal
002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A02 Analytical, structural and metabolic biochemistry / 002A02E Enzymes and enzyme inhibitors / 002A02E02 Oxidoreductases

Discipline
Analytical, structural and metabolic biochemistry Organic chemistry
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
13563759

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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