The influence of first pass metabolism on the development and validation of an IVIVC for metoprolol extended release tablets
- Author
- SIRISUTH, Nattee1 ; EDDINGTON, Natalie D1
[1] Pharmacokinetics Biopharmaceutics Laboratory, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD, United States - Source
European journal of pharmaceutics and biopharmaceutics. 2002, Vol 53, Num 3, pp 301-309 ; ref : 17 ref
- ISSN
- 0939-6411
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Absorption Antihypertenseur Biodisponibilité Bloquant β-adrénergique Comprimé Corrélation Dissolution Effet premier passage Forme pharmaceutique Homme In vitro In vivo Métabolisme Métabolite Métoprolol Normal Pharmacocinétique Prédiction
- Keyword (en)
- Absorption Antihypertensive agent Bioavailability Beta blocking agent Tablet Correlation Dissolution First pass effect Dosage form Human In vitro In vivo Metabolism Metabolite Metoprolol Normal Pharmacokinetics Prediction
- Keyword (es)
- Absorción Antihipertensivo Biodisponibilidad Bloqueador β-adrenérgico Tableta Correlación Disolución Efecto primer paso Forma farmacéutica Hombre In vitro In vivo Metabolismo Metabolito Metoprolol Normal Farmacocinética Predicción
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F05 Antihypertensive agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13637644
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0939-6411(01)00248-X 
https://dx.doi.org/10.1016/S0939-6411(01)00248-X
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