Cyclin-dependent kinase inhibitor (roscovitine) suppresses growth and induces apoptosis by regulating Bcl-x in head and neck squamous cell carcinoma cells
- Author
- MIHARA, Mariko1 ; SHINTANI, Satoru2 ; KIYOTA, Akihisa1 ; MATSUMURA, Tomohiro1 ; WONG, David T. W3
[1] Department of Oral and Maxillofacial Surgery II, Okayama University Dental School, Okayama 700-8525, Japan
[2] Department of Oral and Maxillofacial Surgery, Ehime University School of Medicine, Ehime 791-0295, Japan
[3] Laboratory of Molecular Pathology, Division of Oral Pathology, Department of Oral Medicine and Diagnostic Sciences, Harvard University School of Dental Medicine, Boston, MA 02115, United States - Source
International journal of oncology. 2002, Vol 21, Num 1, pp 95-101 ; ref : 36 ref
- ISSN
- 1019-6439
- Scientific domain
- Medical oncology
- Publisher
- Editorial Academy of the International Journal of Oncology, Athens
- Publication country
- Greece
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Anticancéreux Apoptose Carcinome épidermoïde Gène onc cellulaire Homme Homologie In vitro Inhibition Lignée cellulaire établie Mort cellulaire Multiplication cellulaire Protooncogène Purine Régulation Tête cou Gène bcl2 Gène bclx Inhibiteur kinase dépendant cycline Lignée HSC2 Lignée SCC25 Roscovitine Génétique ORL pathologie Tumeur maligne
- Keyword (en)
- Biological activity Antineoplastic agent Apoptosis Squamous cell carcinoma C-Onc gene Human Homology In vitro Inhibition Established cell line Cell death Cell proliferation Protooncogene Purine Regulation(control) Head and neck Cyclin dependent kinase inhibitor Genetics ENT disease Malignant tumor
- Keyword (es)
- Actividad biológica Anticanceroso Apoptosis Carcinoma epidermoide Gen onc celular Hombre Homología In vitro Inhibición Línea celular establecida Muerte celular Multiplicación celular Protooncogen Purina Regulación Cabeza cuello Genética ORL patología Tumor maligno
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13682636
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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