The novel guanidine ME10092 protects the heart during ischemia-reperfusion
- Author
- DAMBROVA, Maija1 2 ; VEVERIS, Maris2 ; CIRULE, Helena2 ; PUGOVICHS, Osvalds2 ; POST, Claes3 ; LUNDSTEDT, Torbjörn3 4 ; KALVINSH, Ivars2 ; SKOTTNER, Anna1 3 ; WIKBERG, Jarl E. S1
[1] Department of Pharmaceutical Biosciences, Division of Pharmacology, Uppsala University, Box 591, BMC, 751 24, Uppsala, Sweden
[2] Department of Medicinal Chemistry, Latvian Institute of Organic Synthesis, Riga, Latvia
[3] Melacure Therapeutics AB, Uppsala, Sweden
[4] Department of Pharmaceutical Chemistry, Uppsala University, Box 574, 751 23 Uppsala, Sweden - Source
European journal of pharmacology. 2002, Vol 445, Num 1-2, pp 105-113 ; ref : 26 ref
- CODEN
- EJPHAZ
- ISSN
- 0014-2999
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Absorption Activité biologique Animal Antiischémique Appareil circulatoire Artère coronaire Cardioprotecteur Intervalle ST Ischémie Myocarde Pharmacocinétique Rat Relation dose réponse Reperfusion Vaisseau sanguin Vasodilatateur coronarien Voie intraveineuse Voie orale Appareil circulatoire pathologie Cardiopathie coronaire Mammalia Myocarde pathologie Rodentia Vaisseau sanguin pathologie Vertebrata
- Keyword (en)
- Absorption Biological activity Animal Antiïschemic Circulatory system Coronary artery Cardioprotective agent ST interval Ischemia Myocardium Pharmacokinetics Rat Dose activity relation Reperfusion Blood vessel Coronary vasodilator agent Intravenous administration Oral administration Cardiovascular disease Coronary heart disease Mammalia Myocardial disease Rodentia Vascular disease Vertebrata
- Keyword (es)
- Absorción Actividad biológica Animal Antiisquémico Aparato circulatorio Arteria coronaria Cardioprotector Intervalo ST Isquemia Miocardio Farmacocinética Rata Relación dosis respuesta Reperfusión Vaso sanguíneo Vasodilatator coronario Vía intravenosa Vía oral Aparato circulatorio patología Cardiopatía coronaria Mammalia Miocardio patología Rodentia Vaso sanguíneo patología Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F03 Antianginal agents. Coronary vasodilator agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13723344
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0014-2999(02)01596-0 
https://dx.doi.org/10.1016/S0014-2999(02)01596-0
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