Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
- Author
- SANCHEZ-CESPEDES, Montserrat1 ; PARRELLA, Paola1 ; ESTELLER, Manel2 ; NOMOTO, Shuji1 ; TRINK, Barry1 ; ENGLES, James M1 ; WESTRA, William H3 ; HERMAN, James G2 ; SIDRANSKY, David1
[1] Department of Otolaryngology-Head and Neck Surgery, Head and Neck Cancer Research Division, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196, United States
[2] Oncology Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196, United States
[3] Pathology Department, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2196, United States - Source
Cancer research (Baltimore). 2002, Vol 62, Num 13, pp 3659-3662 ; ref : 33 ref
- CODEN
- CNREA8
- ISSN
- 0008-5472
- Scientific domain
- Medical oncology; Pharmacology drugs
- Publisher
- American Association for Cancer Research, Philadelphia, PA
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Adénocarcinome Bronchopulmonaire DNA Expression génique Gène suppresseur tumeur Homme In vitro Mutation somatique Méthylation Pathogénie Promoteur transcription Silence expression génique Séquence nucléotide Séquence riche GC Tumeur maligne Gène LKB1/STK11 Appareil respiratoire pathologie Bronche pathologie Poumon pathologie
- Keyword (en)
- Adenocarcinoma Bronchopulmonary DNA Gene expression Tumor suppressor gene Human In vitro Somatic mutation Methylation Pathogenesis Transcription promoter Gene silencing Nucleotide sequence GC rich sequence Malignant tumor Respiratory disease Bronchus disease Lung disease
- Keyword (es)
- Adenocarcinoma Broncopulmonar DNA Expresión genética Gen supresor tumor Hombre In vitro Mutación somática Metilación Patogenia Promotor transcripción Silencio expresión genética Secuencia nucleótido Secuencia rica GC Tumor maligno Aparato respiratorio patología Bronquio patología Pulmón patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B11 Pneumology / 002B11A Tumors of the respiratory system and mediastinum
- Discipline
- Pulmonology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13755468
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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