Induction of DNA breaks and apoptosis in crosslink-hypersensitive V79 cells by the cytostatic drug β-D-glucosyl-ifosfamide mustard
- Author
- BECKER, R1 ; RITTER, A1 ; EICHHORN, U1 ; LIPS, J1 ; BERTRAM, B2 ; WIESSLER, M2 ; ZDZIENICKA, M. Z3 ; KAINA, B1
[1] Institute of Toxicology, Division of Applied Toxicology, University of Mainz, Obere Zahlbacher Str. 67, 55131 Mainz, Germany
[2] Division of Molecular Toxicology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
[3] Leiden University Medical Center, Department of Radiation Genetics and Chemical Mutagenesis, Wassenaarseweg 72, 2333 Leiden, Netherlands - Source
British journal of cancer. 2002, Vol 86, Num 1, pp 130-135 ; ref : 17 ref
- CODEN
- BJCAAI
- ISSN
- 0007-0920
- Scientific domain
- Medical oncology
- Publisher
- Nature Publishing Group, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Agent alkylant Animal Anticancéreux Apoptose Cassure bicaténaire DNA Glufosfamide Hamster In vitro Lignée V79 Lignée cellulaire établie Mort cellulaire Moutarde à l'azote Réticulation Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Alkylating agent Animal Antineoplastic agent Apoptosis Double strand break DNA Glufosfamide Hamster In vitro V79-Cell line Established cell line Cell death Nitrogen mustard Crosslinking Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Agente alquilante Animal Anticanceroso Apoptosis Ruptura bicatenaria DNA Glufosfamida Hamster In vitro Línea V79 Línea celular establecida Muerte celular Mostaza al nitrógeno Reticulación Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13836192
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjc.6600027 
https://dx.doi.org/10.1038/sj.bjc.6600027
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