A site-specific mutation of tyrosine hydroxylase reduces feedback inhibition by dopamine in genetically modified cells grafted in parkinsonian rats
- Author
- CHANG, J. W1 2 ; LEE, W. Y1 3 ; MILSTIEN, S4 ; KANG, U. J1
[1] Departments of Neurology and Neurobiology, Pharmacology & Physiology, and Committee on Neurobiology, The University of Chicago, Chicago, Illinois, United States
[2] Department of Neurosurgery, BK21 Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea, Republic of
[3] Department of Neurology, SungKyunKwan University, Seoul, Korea, Republic of
[4] Laboratory of Cellular and Molecular Regulation, NIMH, Bethesda, Maryland, United States - Source
Journal of neurochemistry. 2002, Vol 83, Num 1, pp 141-149, 9 p ; ref : 1 p.1/2
- CODEN
- JONRA9
- ISSN
- 0022-3042
- Scientific domain
- Cell biology, histology; Neurology; Physiology, morphology
- Publisher
- Blackwell, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Animal Aromatic-L-amino-acid decarboxylase Dopamine Greffe Gène Interaction génique Mutation Parkinson maladie Rat Thérapie génique Tyrosine 3-monooxygenase Carbon-carbon lyases Carboxy-lyases Catécholamine Encéphale pathologie Enzyme Extrapyramidal syndrome Lyases Maladie dégénérative Mammalia Neurotransmetteur Oxidoreductases Rodentia Système nerveux central pathologie Système nerveux pathologie Vertebrata
- Keyword (en)
- Animal Aromatic-L-amino-acid decarboxylase Dopamine Graft Gene Gene interaction Mutation Parkinson disease Rat Gene therapy Tyrosine 3-monooxygenase Carbon-carbon lyases Carboxy-lyases Catecholamine Cerebral disorder Enzyme Extrapyramidal syndrome Lyases Degenerative disease Mammalia Neurotransmitter Oxidoreductases Rodentia Central nervous system disease Nervous system diseases Vertebrata
- Keyword (es)
- Animal Aromatic-L-amino-acid decarboxylase Dopamina Injerto Gen Interacción génica Mutación Parkinson enfermedad Rata Terapia génica Tyrosine 3-monooxygenase Carbon-carbon lyases Carboxy-lyases Catecolamina Encéfalo patología Enzima Extrapiramidal síndrome Lyases Enfermedad degenerativa Mammalia Neurotransmisor Oxidoreductases Rodentia Sistema nervosio central patología Sistema nervioso patología Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
- Discipline
- Neurology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 13956914
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1046/j.1471-4159.2002.01120.x 
https://dx.doi.org/10.1046/j.1471-4159.2002.01120.x
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