HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action
- Author
- KOPECEK, J1 2 ; KOPECKOVA, P1 2 ; MINKO, T1 ; LU, Z.-R1
[1] Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT, United States
[2] Department of Bioengineering, University of Utah, Salt Lake City, UT, United States - Source
European journal of pharmaceutics and biopharmaceutics. 2000, Vol 50, Num 1, pp 61-81 ; ref : 178 ref
- ISSN
- 0939-6411
- Scientific domain
- Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Anticorps Article synthèse Chimiothérapie Ciblage Déterminant antigénique Essai thérapeutique contrôlé Forme pharmaceutique Gène Homme In vitro In vivo Mécanisme action Méthacrylamide dérivé copolymère Oligonucléotide Perméabilité Photothérapie Polymère conjugué Polymère vecteur Résistance multiple Rétention Technologie pharmaceutique Toxicité Traitement associé Traitement Tumeur solide Vecteur médicament
- Keyword (en)
- Antineoplastic agent Antibody Review Chemotherapy Targeting Antigenic determinant Controlled therapeutic trial Dosage form Gene Human In vitro In vivo Mechanism of action Methacrylamide derivative copolymer Oligonucleotide Permeability Phototherapy Conjugated polymer Control release polymer Multiple resistance Retention Pharmaceutical technology Toxicity Combined treatment Treatment Solid tumor Drug carrier
- Keyword (es)
- Anticanceroso Anticuerpo Artículo síntesis Quimioterapia Blancado Determinante antigénico Ensayo terapéutico controlado Forma farmacéutica Gen Hombre In vitro In vivo Mecanismo acción Metacrilamida derivado copolímero Oligonucleótido Permeabilidad Fototerapia Polímero conjugado Polímero vector Resistencia múltiple Retención Tecnología farmacéutica Toxicidad Tratamiento asociado Tratamiento Tumor sólido Vector medicamento
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A03 Pharmaceutical technology. Pharmaceutical industry
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R04 Combined treatments (chemotherapy of immunotherapy associated with an other treatment)
- Discipline
- General pharmacology Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1397675
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0939-6411(00)00075-8 
https://dx.doi.org/10.1016/S0939-6411(00)00075-8
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