The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol
- Author
- SIEGMUND, Werner1 ; LUDWIG, Karen1 ; GIESSMANN, Thomas1 ; DAZERT, Peter1 ; SCHROEDER, Eike1 ; SPERKER, Bernhard1 ; WARZOK, Rolf1 ; KROEMER, Heyo K1 ; CASCORBI, Ingolf1
[1] Departments of Clinical Pharmacology, General Pharmacology, and Anesthesiology and Intensive Care, Peter Holtz Research Center of Pharmacology and Experimental Therapeutics, and Department of Pathology, Ernst Moritz Arndt University, Germany - Source
Clinical pharmacology and therapeutics. 2002, Vol 72, Num 5, pp 572-583, 12 p ; ref : 38 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Appareil digestif Duodénum Etude comparative Expression génique Glycoprotéine P Génotype Homme Métabolisme Pharmacogénétique Polymorphisme mononucléotide Sonde Talinolol Variant génétique Voie intraveineuse Voie orale Gène mdr1 Génétique
- Keyword (en)
- Digestive system Duodenum Comparative study Gene expression P Glycoprotein Genotype Human Metabolism Pharmacogenetics Single nucleotide polymorphism Probe Talinolol Genetic variant Intravenous administration Oral administration Genetics
- Keyword (es)
- Aparato digestivo Duodeno Estudio comparativo Expresión genética Glicoproteína P Genotipo Hombre Metabolismo Farmacogenética Polimorfismo mononucleótido Sonda Talinolol Variante genética Vía intravenosa Vía oral Genética
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14030500
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1067/mcp.2002.127739 
https://dx.doi.org/10.1067/mcp.2002.127739
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