The new compound, LASSBio 294, increases the contractility of intact and saponin-skinned cardiac muscle from Wistar rats
- Author
- SUDO, R. T1 ; ZAPATA-SUDO, G1 ; BARREIRO, E. J2
[1] Departamento de Farmacologia Básica e Clínica, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Bloco J, Sala 14, Cidade Universitària, Rio de Janeiro, 21941-590 RJ, Brazil
[2] Laboratório de Avaliação e Síntese de Substâncias Bioativas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, RJ, Brazil - Source
British journal of pharmacology. 2001, Vol 134, Num 3, pp 603-613 ; ref : 23 ref
- CODEN
- BJPCBM
- ISSN
- 0007-1188
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, Basingstoke
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Animal Appareil circulatoire Calcium Cardiotonique Courant ionique In vitro Intracellulaire Muscle papillaire Myocarde Mécanisme action Oreillette Rat Réticulum sarcoplasmique Ventricule cardiaque L 294 Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Animal Circulatory system Calcium Cardiotonic agent Ionic current In vitro Intracellular Papillary muscle Myocardium Mechanism of action Atrium Rat Sarcoplasmic reticulum Heart ventricle Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Animal Aparato circulatorio Calcio Cardiotónico Corriente iónica In vitro Intracelular Músculo papilar Miocardio Mecanismo acción Orejuela Rata Retículo sarcoplásmico Ventrículo cardíaco Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02F Cardiovascular system / 002B02F01 Cardiotonic agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14061415
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/sj.bjp.0704291 
https://dx.doi.org/10.1038/sj.bjp.0704291
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