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The inhibitory effect of simvastatin on growth in malignant gliomas - with special reference to its local application with fibrin glue spray in vivo

Author
MURAKAMI, Masaji1 ; GOTO, Tomoaki1 ; SAITO, Yoshiki1 ; GOTO, Satoshi1 ; KOCHI, Masato1 ; USHIO, Yukitaka1
[1] Department of Neurosurgery, Kumamoto University School of Medicine, 1-1-1 Honjo, Kumamoto 860-8556, Japan
Source

International journal of oncology. 2001, Vol 19, Num 3, pp 525-531 ; ref : 37 ref

ISSN
1019-6439
Scientific domain
Medical oncology
Publisher
Editorial Academy of the International Journal of Oncology, Athens
Publication country
Greece
Document type
Article
Language
English
Keyword (fr)
Animal Anticancéreux Chimiothérapie Fibrine Forme libération contrôlée Gliome malin Homme Hydroxymethylglutaryl-CoA reductase In vitro In vivo Inhibiteur enzyme Inhibition Lignée cellulaire établie Multiplication cellulaire Rat Simvastatine Statine dérivé Traitement Voie locale Colle Lignée U 251MG Lignée U 87MG Enzyme Mammalia Oxidoreductases Rodentia Système nerveux central pathologie Système nerveux pathologie Tumeur maligne Vertebrata
Keyword (en)
Animal Antineoplastic agent Chemotherapy Fibrin Controlled release form Malignant glioma Human Hydroxymethylglutaryl-CoA reductase In vitro In vivo Enzyme inhibitor Inhibition Established cell line Cell proliferation Rat Simvastatin Statin derivative Treatment Local administration Enzyme Mammalia Oxidoreductases Rodentia Central nervous system disease Nervous system diseases Malignant tumor Vertebrata
Keyword (es)
Animal Anticanceroso Quimioterapia Fibrina Forma liberación controlada Glioma maligno Hombre Hydroxymethylglutaryl-CoA reductase In vitro In vivo Inhibidor enzima Inhibición Línea celular establecida Multiplicación celular Rata Simvastatina Statina derivado Tratamiento Vía local Enzima Mammalia Oxidoreductases Rodentia Sistema nervosio central patología Sistema nervioso patología Tumor maligno Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
14082148

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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