Assays to predict the genotoxicity of the chromosomal mutagen etoposide - focussing on the best assay
- Author
- TURNER, S. D1 ; WIJNHOVEN, S. W. P2 ; TINWELL, H3 ; LASHFORD, L. S1 4 ; RAFFERTY, J. A1 ; ASHBY, J3 ; VRIELING, H2 ; FAIRBAIRN, L. J1
[1] Gene Therapy Group, Christie Hospital (NHS) Trust, Wilmslow Road, Manchester M20 4BX, United Kingdom
[2] Department of Radiation Genetics and Chemical Mutagenesis-MGC, Leiden University Medical Centre, P.O. Box 9503, 2300 RA Leiden, Netherlands
[3] Zeneca Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire SK10 4TJ, United Kingdom
[4] Paterson Institute for Cancer Research and Academic Department of Paediatric Oncology, Christie Hospital (NHS) Trust, Wilmslow Road, Manchester M20 4BX, United Kingdom - Source
Mutation research. Genetic toxicology and environmental mutagenesis. 2001, Vol 493, Num 1-2, pp 139-147 ; ref : 40 ref
- ISSN
- 1383-5718
- Scientific domain
- Environment; Genetics; Toxicology
- Publisher
- Elsevier, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Keyword (fr)
- Aberration chromosomique Adenine phosphoribosyltransferase Etoposide Gène In vivo Lésion Modèle animal Mutation Souris Test comète Test micronucléus Test mutagénicité Toxicité Anticancéreux Enzyme Glycosyltransferases Mammalia Pentosyltransferases Rodentia Transferases Vertebrata
- Keyword (en)
- Chromosomal aberration Adenine phosphoribosyltransferase Etoposide Gene In vivo Lesion Animal model Mutation Mouse Comet assay Micronucleus test Mutagenicity testing Toxicity Antineoplastic agent Enzyme Glycosyltransferases Mammalia Pentosyltransferases Rodentia Transferases Vertebrata
- Keyword (es)
- Aberración cromosómica Adenine phosphoribosyltransferase Etopósido Gen In vivo Lesión Modelo animal Mutación Ratón Cometa prueba Prueba micronúcleo Prueba mutagenicidad Toxicidad Anticanceroso Enzima Glycosyltransferases Mammalia Pentosyltransferases Rodentia Transferases Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U10 Miscellaneous (drug allergy, mutagens, teratogens...)
- Discipline
- Drugs toxicity and drug intoxications Toxicology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14099383
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S1383-5718(01)00170-X 
https://dx.doi.org/10.1016/S1383-5718(01)00170-X
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