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Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro : Can dextromethorphan be used as a dual probe for both CYP2D6 and CYP3A activities?

Author
AIMING YU1 ; HAINING, Robert L1
[1] Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, West Virginia, United States
Source

Drug metabolism and disposition. 2001, Vol 29, Num 11, pp 1514-1520 ; ref : 40 ref

CODEN
DMDSAI
ISSN
0090-9556
Scientific domain
Pharmacology drugs
Publisher
American Society for Pharmacology and Experimental Therapeutics, Bethesda, MD
Publication country
United States
Document type
Article
Language
English
Keyword (fr)
Antitussif Appareil digestif Cytochrome P450 Dextrométhorphane Déméthylation Expression génique Foie Homme Isozyme Microsome Morphinane dérivé Métabolisme Métabolite Opiacés
Keyword (en)
Antitussive agent Digestive system Cytochrome P450 Dextromethorphan Demethylation Gene expression Liver Human Isozyme Microsome Morphinan derivatives Metabolism Metabolite Opiates
Keyword (es)
Antitusivo Aparato digestivo Citocromo P450 Dextrometorfano Desmetilación Expresión genética Hígado Hombre Isozima Microsoma Morphinano derivado Metabolismo Metabolito Opiados
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02D Respiratory system

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
14107575

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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