Pestalone, a new antibiotic produced by a marine fungus in response to bacterial challenge
- Author
- CUETO, Mercedes1 ; JENSEN, Paul R1 ; KAUFFMAN, Chris1 ; FENICAL, William2 ; LOBKOVSKY, Emil2 ; CLARDY, Jon2
[1] Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093-0204, United States
[2] Department of Chemistry and Chemical Biology, Cornell University, Ithaca, New York 14850, United States - Source
Journal of natural products (Print). 2001, Vol 64, Num 11, pp 1444-1446 ; ref : 12 ref
- CODEN
- JNPRDF
- ISSN
- 0163-3864
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
/
American Society of Pharmacognosy, Glendale, AZ
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Aldéhyde Aldéhydophénols Analyse structurale Antibactérien Antibiotique Anticancéreux Bactérie Benzophénone dérivé Cellule tumorale Composé benzénique Culture mixte Cytotoxicité Cétonephénols Enterococcus faecium Halogénophénols In vitro Isolement Lignée cellulaire Milieu marin Origine microbienne Pestalotiopsis Staphylococcus aureus Benzaldéhyde(2-[3,5-dichloro-2-hydroxy-6-méthoxy-4-méthylbenzoyl]-4,6-dihydroxy-3-isoprényl) Pestalone Souche résistante méticilline Souche résistante vancomycine Bahamas Chlore Composé organique Fungi Imperfecti Fungi Micrococcaceae Micrococcales Streptococcaceae Thallophyta Amérique Centrale Amérique Antilles
- Keyword (en)
- Biological activity Aldehyde Aldehydophenols Structural analysis Antibacterial agent Antibiotic Antineoplastic agent Bacteria Benzophenone derivatives Tumor cell Benzenic compound Mixed cropping Cytotoxicity Ketophenols Enterococcus faecium Halophenols In vitro Isolation Cell line Marine environment Microbial origin Pestalotiopsis Staphylococcus aureus Bahamas Chlorine Organic compounds Fungi Imperfecti Fungi Micrococcaceae Micrococcales Streptococcaceae Thallophyta Central America America West Indies
- Keyword (es)
- Actividad biológica Aldehído Aldehidofenoles Análisis estructural Antibacteriano Antibiótico Anticanceroso Bacteria Benzofenona derivado Célula tumoral Compuesto bencénico Cultivo mixto Citotoxicidad Cetofenoles Enterococcus faecium Halofenoles In vitro Aislamiento Línea celular Medio marino Origen microbiano Pestalotiopsis Staphylococcus aureus Bahamas Cloro Compuesto orgánico Fungi Imperfecti Fungi Micrococcaceae Micrococcales Streptococcaceae Thallophyta America central America Antillas
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A05 Microbiology / 002A05F Applied microbiology / 002A05F03 Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents / 002A05F03B Antibiotics (antibacterial agents, antifungal agents)
- Discipline
- Microbiology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14133305
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/np0102713 
https://dx.doi.org/10.1021/np0102713
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