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The neuroprotective actions of FK506 binding protein ligands: neuronal survival is triggered by de novo RNA synthesis, but is independent of inhibition of JNK and calcineurin

Author
KLETTNER, A1 ; BAUMGRASS, R2 ; ZHANG, Y2 ; FISCHER, G2 ; BÜRGER, E3 ; HERDEGEN, T1 ; MIELKE, K4
[1] Institute of Pharmacology, Christian-Albrechts-University, Hospitalstrasse 4, 24105 Kiel, Germany
[2] Max-Planck Research Unit for Enzymology of Protein Folding, Halle/Saale, Germany
[3] Department of CNS Research, Boehringer-Ingelheim Pharma KG, Ingelheim, Germany
[4] Department of Neurology, Center of Clinical Research, Ulm, Germany
Source

Molecular brain research. 2001, Vol 97, Num 1, pp 21-31 ; ref : 76 ref

ISSN
0169-328X
Scientific domain
Biochemistry, molecular biology, biophysics; Genetics; Neurology; Physiology, morphology
Publisher
Elsevier, Amsterdam
Publication country
Netherlands
Document type
Article
Language
English
Keyword (fr)
Calcineurine Immunodépresseur In vitro Inhibiteur enzyme Ligand Lignée cellulaire Mort cellulaire Neurone Neuroprotecteur Protéine liaison Rat Synthèse RNA Lignée PC12 Mammalia Rodentia Vertebrata
Keyword (en)
Calcineurin Immunosuppressive agent In vitro Enzyme inhibitor Ligand Cell line Cell death Neuron Neuroprotective agent Binding protein Rat RNA synthesis Mammalia Rodentia Vertebrata
Keyword (es)
Calcineurina Inmunodepresor In vitro Inhibidor enzima Ligando Línea celular Muerte celular Neurona Neuroprotector Proteína enlace Rata Síntesis RNA Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B10 Neuroprotective agent

Discipline
Pharmacological treatments
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
14139441

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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