The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
- Author
- YI YANG1 ; HENTATI, Afif1 ; COLE, Natalie1 ; GASCON, Generoso3 ; YAGMOUR, Ayesha4 ; BEN-HAMIDA, Mongi5 ; PERICAK-VANCE, Margaret6 ; HENTATI, Faycal5 ; SIDDIQUE, Teepu1 7 8 ; DENG, Han-Xiang1 ; DABBAGH, Omar2 ; SASAKI, Toru1 ; HIRANO, Makito1 ; HUNG, Wu-Yen1 ; OUAHCHI, Karim1 ; JIANHUA YAN1 ; AZIM, Anser C1
[1] Department of Neurology, Northwestern University Medical School, Chicago, Illinois, United States
[2] King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
[3] Division of Pediatric Neurology, Brown University, Providence, Rhode Island, United States
[4] King Fahad Military Hospital, Jeddah, Saudi Arabia
[5] Institute of Neurology, Tunis, Tunisia
[6] Medical Genetics, Duke University Medical Center, Durham, North Carolina, United States
[7] Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, Illinois, United States
[8] Northwestern University Institute of Neuroscience, Chicago, Illinois, United States - Source
Nature genetics. 2001, Vol 29, Num 2, pp 160-165 ; ref : 50 ref
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Guanine nucléotide Gène Mutation Protéine A Sclérose latérale amyotrophique Maladie dégénérative Moelle épinière pathologie Système nerveux central pathologie Système nerveux pathologie
- Keyword (en)
- Guanine nucleotide Gene Mutation Protein A Amyotrophic lateral sclerosis Degenerative disease Spinal cord disease Central nervous system disease Nervous system diseases
- Keyword (es)
- Guanina nucleótido Gen Mutación Proteína A Esclerosis lateral amiotrófica Enfermedad degenerativa Médula espinal patología Sistema nervosio central patología Sistema nervioso patología
- Classification
- Pascal
- 002 Biological and medical sciences / 002A Fundamental and applied biological sciences. Psychology / 002A04 Molecular and cellular biology / 002A04C Molecular genetics / 002A04C02 Genes. Genome
- Discipline
- Molecular and cell biology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14158895
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/ng1001-160 
https://dx.doi.org/10.1038/ng1001-160
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