Evaluation of the genetic component of variability in CYP3A4 activity : a repeated drug administration method
- Author
- ÖZDEMIR, V1 2 ; KALOW, W1 ; TANG, B.-K1 ; PATERSON, A. D2 ; WALKER, S. E1 ; ENDRENYI, L1 ; KASHUBA, A. D. M3
[1] Departments of Pharmacology and Pharmaceutical Sciences, University of Toronto, Canada
[2] Neurogenetics Section, Clarke Division, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Canada
[3] School of Pharmacy, University of North Carolina at Chapel Hill, North Carolina, United States - Source
Pharmacogenetics (London). 2000, Vol 10, Num 5, pp 373-388 ; ref : 1 p.3/4
- ISSN
- 0960-314X
- Scientific domain
- Genetics; Pharmacology drugs
- Publisher
- Lippincott Williams and Wilkins, Hagerstown, MD
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité enzymatique Article synthèse Ciclosporine Cytochrome P450 Erythromycine Midazolam Médicament Pharmacocinétique Pharmacogénétique Phénotype hydroxylateur Régulation Variabilité génétique Cytochrome CYP3A4 Benzodiazépine dérivé Immunodépresseur
- Keyword (en)
- Enzymatic activity Review Ciclosporin Cytochrome P450 Erythromycin Midazolam Drug Pharmacokinetics Pharmacogenetics Hydroxylator phenotype Regulation(control) Genetic variability Benzodiazepine derivatives Immunosuppressive agent
- Keyword (es)
- Actividad enzimática Artículo síntesis Ciclosporina Citocromo P450 Eritromicina Midazolam Medicamento Farmacocinética Farmacogenética Fenotipo hidroxilador Regulación Variabilidad genética Benzodiazepina derivado Inmunodepresor
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1430015
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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