Stereospecific analysis of omeprazole in human plasma as a probe for CYP2C19 phenotype
- Author
- KANAZAWA, Hideko1 ; OKADA, Akiko1 ; HIGAKI, Megumu2 ; YOKOTA, Hiromitsu3 ; MASHIGE, Fumiko3 ; NAKAHARA, Kazuhiko3
[1] Department of Physical Chemistry, Kyoritsu College of Pharmacy, Shihakoen 1-5-30, Minato-ku, Tokyo 105-8512, Japan
[2] Institute of Medical Science, St. Marianna University School of Medicine, Sugao 2-16-1, Miyamae-ku, Kanagawa 216-8512, Japan
[3] Department of Laboratory Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-8655, Japan - Issue title
- The importance of separation techniques for pharmaceutical, biomedical and environmental analysis
- Author (monograph)
- HAGINAKA, Jun (Editor)1 ; LINGEMAN, Henk (Editor)2
[1] Faculty of Pharmaceutical Sciences, Mukogawa Women's University, 11-68, Koshien Kyuba-cho, Nishinomiya 663-8179, Hyogo, Japan
[2] Department of Analytical Chemistry, Free University, 1081 HV Amsterdam, Netherlands - Source
Journal of pharmaceutical and biomedical analysis. 2003, Vol 30, Num 6, pp 1817-1824, 8 p ; ref : 15 ref
- CODEN
- JPBADA
- ISSN
- 0731-7085
- Scientific domain
- Medical laboratory techniques; Pharmacology drugs
- Publisher
- Elsevier Science, Amsterdam
- Publication country
- Netherlands
- Document type
- Article
- Language
- English
- Author keyword
- CYP2C19 Circular dichroism detection Cytochrome P-450 LCIMS Omeprazole Proton pump inhibitor Stereospecific analysis
- Keyword (fr)
- Analyse quantitative Benzimidazole dérivé Chromatographie phase liquide Cytochrome P450 Dichroïsme circulaire Enantiomère Foie Gène Génétique Homme Inhibiteur pompe proton Isomère optique Liquide biologique Microsome Métabolisme Méthode analyse Oméprazole Pharmacocinétique Plasma sanguin Polymorphisme Spectrométrie masse Stéréoisomère Stéréospécificité Voie orale Cytochrome CYP2C19
- Keyword (en)
- Quantitative analysis Benzimidazole derivatives Liquid chromatography Cytochrome P450 Circular dichroism Enantiomer Liver Gene Genetics Human Proton pump inhibitor Optical isomer Biological fluid Microsome Metabolism Analysis method Omeprazole Pharmacokinetics Blood plasma Polymorphism Mass spectrometry Stereoisomer Stereospecificity Oral administration
- Keyword (es)
- Análisis cuantitativo Benzimidazol derivado Cromatografía fase líquida Citocromo P450 Dicroismo circular Enantiómero Hígado Gen Genética Hombre Inhibidor bomba protón Isómero óptico Líquido biológico Microsoma Metabolismo Método análisis Omeprazol Farmacocinética Plasma sanguíneo Polimorfismo Espectrometría masa Estereoisómero Estereoespecificidad Vía oral
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A02 Analysis
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14410462
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0731-7085(02)00524-1 
https://dx.doi.org/10.1016/S0731-7085(02)00524-1
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