Requirement of nucleobase proximal to CpG dinucleotide for immunostimulatory activity of synthetic CpG DNA
- Author
- DONG YU1 ; KANDIMALLA, Ekambar R1 ; QIUYAN ZHAO1 ; BHAGAT, Lakshmi1 ; YANPING CONG1 ; AGRAWAL, Sudhir1
[1] Hybridon, Inc., 345 Vassar Street, Cambridge, MA 02139, United States - Source
Bioorganic & medicinal chemistry. 2003, Vol 11, Num 3, pp 459-464, 6 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité biologique Animal Culture cellulaire Cytokine DNA Dinucléotide Désoxyribonucléotide Immunostimulant In vitro In vivo Interleukine 12 Interleukine 6 Mononucléaire Oligodésoxyribonucléotide Phosphoramidite organique Rate Souris Splénocyte Spécificité séquence Synthèse chimique Séquence nucléotide Thiophosphate organique Site abasique Mammalia Rodentia Vertebrata
- Keyword (en)
- Biological activity Animal Cell culture Cytokine DNA Dinucleotide Deoxyribonucleotide Immunostimulant agent In vitro In vivo Interleukin 12 Interleukin 6 Mononuclear cell Oligodeoxyribonucleotide Organic phosphoramidite Spleen Mouse Splenocyte Sequence specificity Chemical synthesis Nucleotide sequence Organic thiophosphate Mammalia Rodentia Vertebrata
- Keyword (es)
- Actividad biológica Animal Cultivo celular Citoquina DNA Dinucleótido Desoxirribonucleótido Inmunoestimulante In vitro In vivo Interleuquina 12 Interleuquina 6 Mononuclear Oligodesoxirribonucleótido Fosforamidito orgánico Bazo Ratón Esplenocito Espicificidad secuencia Síntesis química Secuencia nucleótido Tiofosfato orgánico Mammalia Rodentia Vertebrata
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02Q Immunomodulators
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14458243
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0968-0896(02)00430-3 
https://dx.doi.org/10.1016/S0968-0896(02)00430-3
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