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A novel trivalent cation chelator Feralex dissociates binding of aluminum and iron associated with hyperphosphorylated τ of Alzheimer's disease

Author
SHIN, Ryong-Woon1 ; KRUCK, Theo P. A2 3 ; MURAYAMA, Harunobu4 ; KITAMOTO, Tetsuyuki1
[1] Department of Neurological Science, Tohoku University School of Medicine, 2-1 Seiryo-machi, Sendai 980-8575, Japan
[2] Department of Physiology, University of Toronto, Toronto, Ontario, M5S-1A1, Canada
[3] Neurogenetics Laboratory, Surrey Place Centre, 2 Surrey Place, Toronto, Ontario, M5 S-2C2, Canada
[4] Department of Pathology, Sendai City Hospital, Sendai 984-8501, Japan
Source

Brain research. 2003, Vol 961, Num 1, pp 139-146, 8 p ; ref : 30 ref

CODEN
BRREAP
ISSN
0006-8993
Scientific domain
Neurology; Physiology, morphology
Publisher
Elsevier, Amsterdam / Elsevier, London / Elsevier, New York, NY
Publication country
Netherlands
Document type
Article
Language
English
Author keyword
Aluminum Alzheimer's disease Chelation Feralex-G and desferrioxamine Iron PHF T protein
Keyword (fr)
Aluminium Cation trivalent Chélation Démence Alzheimer Fer Phosphorylation Protéine tau Encéphale pathologie Maladie dégénérative Système nerveux central pathologie Système nerveux pathologie
Keyword (en)
Aluminium Trivalent cation Chelation Alzheimer disease Iron Phosphorylation Tau protein Cerebral disorder Degenerative disease Central nervous system disease Nervous system diseases
Keyword (es)
Aluminio Catión trivalente Quelación Demencia Alzheimer Hierro Fosforilación Proteína tau Encéfalo patología Enfermedad degenerativa Sistema nervosio central patología Sistema nervioso patología
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B17 Neurology / 002B17G Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases

Discipline
Neurology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
14469799

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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