Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia
- Author
- STAM, Ronald W; DEN BOER, Monique L; MEIJERINK, Jules P. P; EBUS, Marli E. G; PETERS, Godefridus J; NOORDHUIS, Paul; JANKA-SCHAUB, Gritta E; ARMSTRONG, Scott A; KORSMEYER, Stanley J; PIETERS, Rob
Cooperative Acute Lymphoblastic Leukemia (COALL) study group, Hamburg, Germany
Department of Medical Oncology, Vrye Universiteit University Medical Center, Amsterdam, Netherlands
Department of Pediatric Oncology, the Department of Cancer Immunology and AIDS, and the Howard Hughes Medical Institute, Dana-Farber Cancer Institute, Boston, MA, United States
Division of Pediatric Hematology/Oncology, Children's Hospital, Boston, MA, United States
Harvard Medical School, Boston, MA, United States
University Hospital Rotterdam/Sophia Children's Hospital, Department of Pediatric Oncology/Hematology, Erasmus Medical Center, Rotterdam, Netherlands - Source
Blood. 2003, Vol 101, Num 4, pp 1270-1276, 7 p ; ref : 35 ref
- ISSN
- 0006-4971
- Scientific domain
- Medical oncology; Hematology
- Publisher
- The Americain Society of Hematology, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité enzymatique Aigu Anticancéreux Antimétabolite Chimiothérapie Cytarabine Enzyme Expression génique Leucémie lymphoblastique Métabolisme Nourrisson Pyrimidine nucléoside RNA messager Gène MLL Homme Hémopathie maligne Lymphoprolifératif syndrome
- Keyword (en)
- Enzymatic activity Acute Antineoplastic agent Antimetabolic Chemotherapy Cytarabine Enzyme Gene expression Acute lymphocytic leukemia Metabolism Infant Pyrimidine nucleoside Messenger RNA Human Malignant hemopathy Lymphoproliferative syndrome
- Keyword (es)
- Actividad enzimática Agudo Anticanceroso Antimetabólito Quimioterapia Citarabina Enzima Expresión genética Leucemia linfoblástica Metabolismo Lactante Pirimidina nucleósido RNA mensajero Hombre Hemopatía maligna Linfoproliferativo síndrome
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R02 Chemotherapy
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B19 Hematologic and hematopoietic diseases / 002B19B Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
- Discipline
- Blood diseases Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14530473
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1182/blood-2002-05-1600 
https://dx.doi.org/10.1182/blood-2002-05-1600
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