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The modulation of irinotecan-induced diarrhoea and pharmacokinetics by three different classes of pharmacologic agents

Author
CHOWBAY, Balram1 ; SHARMA, Amarnath2 ; ZHOU, Qing-Yu1 ; YIN BUN CHEUNG3 ; LEE, Edmund J. D4
[1] Laboratory of Clinical Pharmacology, Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore
[2] Groton Laboratories, Pfizer Inc, Groton, CT 06340, United States
[3] Biostatistics Unit, Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore
[4] Department of Pharmacology, Faculty of Medicine, National University of Singapore, Singapore
Source

Oncology reports. 2003, Vol 10, Num 3, pp 745-751, 7 p ; ref : 20 ref

ISSN
1021-335X
Scientific domain
Medical oncology
Publisher
[S.n.], Athens
Publication country
Greece
Document type
Article
Language
English
Author keyword
CPT-11 SN-38 charcoal pharmacokinetics β-glucuronidase
Keyword (fr)
Acide valproïque Animal Antidiarrhéique Ceftriaxone Charbon bois Chimioprophylaxie Céphalosporine dérivé DNA topoisomerase Diarrhée Inhibiteur enzyme Irinotécan Pharmacocinétique Prévention Rat Toxicité Voie intraveineuse Voie orale β-Lactamines Pyrano indolizino quinoléine dérivé Appareil digestif pathologie Enzyme Intestin pathologie Isomerases Mammalia Rodentia Vertebrata
Keyword (en)
Valproic acid Animal Antidiarrheal agent Ceftriaxone Charcoal Chemoprophylaxis Cephalosporin derivatives DNA topoisomerase Diarrhea Enzyme inhibitor Irinotecan Pharmacokinetics Prevention Rat Toxicity Intravenous administration Oral administration β-Lactams Digestive diseases Enzyme Intestinal disease Isomerases Mammalia Rodentia Vertebrata
Keyword (es)
Acido valproico Animal Antidiarreico Ceftriaxona Carbón madera Quimioprofilaxis Cefalosporina derivado DNA topoisomerase Diarrea Inhibidor enzima Irinotecán Farmacocinética Prevención Rata Toxicidad Vía intravenosa Vía oral β-Lactams Aparato digestivo patología Enzima Intestino patología Isomerases Mammalia Rodentia Vertebrata
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02U Drug toxicity and drugs side effects treatment / 002B02U04 Toxicity: digestive system

Discipline
Drugs toxicity and drug intoxications Toxicology
Origin
Inist-CNRS
Database
PASCAL
INIST identifier
14622059

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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