Quinidine as a probe for CYP3A4 activity : Intrasubject variability and lack of correlation with probe-based assays for CYP1A2, CYP2C9, CYP2C19, and CYP2D6
- Author
- DAMKIER, P1 ; BRØSEN, K1
[1] Clinical Pharmacology, Institute of Public Health, University of Southern Denmark, Odense University, Denmark - Source
Clinical pharmacology and therapeutics. 2000, Vol 68, Num 2, pp 199-209 ; ref : 49 ref
- CODEN
- CLPTAT
- ISSN
- 0009-9236
- Scientific domain
- Pharmacology drugs
- Publisher
- Nature Publishing, New York, NY
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Activité enzymatique Cytochrome P450 Dose unique Homme Individu sain Isozyme Métabolisme Méthode mesure Pharmacocinétique Quinidine Voie orale Cytochrome CYP3A4
- Keyword (en)
- Enzymatic activity Cytochrome P450 Single dose Human Healthy subject Isozyme Metabolism Measurement method Pharmacokinetics Quinidine Oral administration
- Keyword (es)
- Actividad enzimática Citocromo P450 Dosis única Hombre Individuo sano Isozima Metabolismo Método medida Farmacocinética Quinidina Vía oral
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02A General pharmacology / 002B02A05 Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions
- Discipline
- General pharmacology
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1483357
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1067/mcp.2000.108532 
https://dx.doi.org/10.1067/mcp.2000.108532
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