Synthesis and structure-antifungal activity relationships of 3-aryl-5-alkyl-2,5-dihydrofuran-2-ones and their carbanalogues: Further refinement of tentative pharmacophore group
- Author
- POUR, Milan1 ; SPULAK, Marcel1 ; BALSANEK, Vojtech1 ; KUNES, Jiri1 ; KUBANOVA, Petra2 ; BUCHTA, Vladimir2
[1] Laboratory of Structure and Interactions of Biologically Active Molecules, Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
[2] Department of Biological and Medical Sciences, Faculty of Pharmacy, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic - Source
Bioorganic & medicinal chemistry. 2003, Vol 11, Num 13, pp 2843-2866, 24 p
- ISSN
- 0968-0896
- Scientific domain
- Biochemistry, molecular biology, biophysics; Pharmacology drugs
- Publisher
- Elsevier Science, Oxford
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Absidia corymbifera Antifongique Aspergillus fumigatus Benzène dérivé Composé monocyclique Cycle 5 chaînons Hétérocycle oxygène In vitro Indole dérivé Lactone Naphtalène dérivé Relation structure activité Synthèse chimique Adamantane dérivé Benzo[b]thiophène dérivé Cyclopent-2-énone(2-aryl) Furan-2-one(3-adamantyl-5-alkyl) Furan-2-one(5-alkyl-3-aryl) Incrustosporine Fungi Imperfecti Fungi Phycomycetes Thallophyta
- Keyword (en)
- Absidia corymbifera Antifungal agent Aspergillus fumigatus Benzene derivatives Monocyclic compound Five membered ring Oxygen heterocycle In vitro Indole derivatives Lactone Naphthalene derivatives Structure activity relation Chemical synthesis Fungi Imperfecti Fungi Phycomycetes Thallophyta
- Keyword (es)
- Absidia corymbifera Antifúngico Aspergillus fumigatus Benceno derivado Compuesto monocíclico Ciclo 5 eslabones Heterociclo oxígeno In vitro Indol derivado Lactona Naftaleno derivado Relación estructura actividad Síntesis química Fungi Imperfecti Fungi Phycomycetes Thallophyta
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02S Antibiotics. Antiinfectious agents. Antiparasitic agents / 002B02S04 Antifungal agents
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14852031
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1016/S0968-0896(03)00220-7 
https://dx.doi.org/10.1016/S0968-0896(03)00220-7
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