Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents
- Author
- KUMAR, Srinivas K1 ; HAGER, Erin1 ; PETTIT, Catherine1 ; GURULINGAPPA, Hallur1 ; DAVIDSON, Nancy E1 ; KHAN, Saeed R1
[1] Division of Experimental Therapeutics, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231, United States - Source
Journal of medicinal chemistry (Print). 2003, Vol 46, Num 14, pp 2813-2815, 3 p ; ref : 34 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Boronique acide Cellule tumorale Composé benzénique Enone Epithélium Glande mammaire Homme In vitro Inhibition Lignée cellulaire Multiplication cellulaire Relation structure activité Synthèse chimique Chalcone(3-bromo-4p-[(dihydroxyboryl)méthoxy]-4-fluoro) Chalcone(4p-[(dihydroxyboryl)méthoxy]-4-iodo) Lignée MCF7 Lignée MDAMB231 Bore Composé organique Halogène Composé organique
- Keyword (en)
- Antineoplastic agent Boronic acids Tumor cell Benzenic compound Enone Epithelium Mammary gland Human In vitro Inhibition Cell line Cell proliferation Structure activity relation Chemical synthesis Boron Organic compounds Halogen Organic compounds
- Keyword (es)
- Anticanceroso Célula tumoral Compuesto bencénico Enona Epitelio Glándula mamaria Hombre In vitro Inhibición Línea celular Multiplicación celular Relación estructura actividad Síntesis química Boro Compuesto orgánico Halógeno Compuesto orgánico
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 14919311
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm030213+ 
https://dx.doi.org/10.1021/jm030213+
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