Gold(III) complexes as potential antitumor agents : Solution chemistry and cytotoxic properties of some selected gold(III) compounds
- Author
- MESSORI, Luigi1 ; ABBATE, Francesco1 ; MARCON, Giordana1 ; ORIOLI, Pierluigi1 ; FONTANI, Marco2 ; MINI, Enrico3 ; MAZZEI, Teresita3 ; CAROTTI, Stefania3 ; O'CONNELL, Tim1 ; ZANELLO, Piero2
[1] Department of Chemistry, University of Florence, Florence, Italy
[2] Department of Pharmacology, University of Florence, Florence, Italy
[3] Department of Chemistry, University of Siena, Siena, Italy - Source
Journal of medicinal chemistry (Print). 2000, Vol 43, Num 19, pp 3541-3548 ; ref : 31 ref
- CODEN
- JMCMAR
- ISSN
- 0022-2623
- Scientific domain
- Pharmacology drugs
- Publisher
- American Chemical Society, Washington, DC
- Publication country
- United States
- Document type
- Article
- Language
- English
- Keyword (fr)
- Anticancéreux Cellule tumorale Complexe chloro Complexe perchlorato Composé crown azote Coordinat bidenté Coordinat organique Coordinat tridenté Coordinat tétradenté Cytotoxicité Homme Hétérocycle azote In vitro Lignée cellulaire Or III Complexe Ovaire Propriété électrochimique Pyridine dérivé Relation structure activité Résistance Réversibilité Synthèse chimique 2,2p:6p,2s-Terpyridine Diéthylènetriamine Ethylènediamine Phénanthridine Tétraaza-14-crown-4 Métal transition Complexe Métal trivalent Complexe
- Keyword (en)
- Antineoplastic agent Tumor cell Chloro complex Perchlorato complex Nitrogen crown compound Bidentate ligand Organic ligand Tridentate ligand Tetradentate ligand Cytotoxicity Human Nitrogen heterocycle In vitro Cell line Gold III Complexes Ovary Electrochemical properties Pyridine derivatives Structure activity relation Resistance Reversibility Chemical synthesis Transition metal Complexes Trivalent metal Complexes
- Keyword (es)
- Anticanceroso Célula tumoral Complejo cloro Complejo perclorato Compuesto crown nitrógeno Ligando bidentado Ligando orgánico Ligando tridentado Ligando tetradentado Citotoxicidad Hombre Heterociclo nitrógeno In vitro Línea celular Oro III Complejo Ovario Propiedad electroquímica Piridina derivado Relación estructura actividad Resistencia Reversibilidad Síntesis química Metal transición Complejo Metal trivalente Complejo
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02R Antineoplastic agents / 002B02R01 General aspects
- Discipline
- Pharmacological treatments
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1508252
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1021/jm990492u 
https://dx.doi.org/10.1021/jm990492u
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