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Metabolism of citalopram enantiomers in CYP2Cl9/CYP2D6 phenotyped panels of healthy Swedes

Author
HERRLIN, Karin1 ; YASUI-FURUKORI, Norio1 ; TYBRING, Gunnel1 ; WIDEN, Jolanta1 ; GUSTAFSSON, Lars L1 ; BERTILSSON, Leif1
[1] Division of Clinical Pharmacology at Department of Medicine Laboratory, Karolinska Institutet at Huddinge University Hospital, Huddinge, Sweden
Source

British journal of clinical pharmacology. 2003, Vol 56, Num 4, pp 415-421, 7 p ; ref : 27 ref

CODEN
BCPHBM
ISSN
0306-5251
Scientific domain
Pharmacology drugs
Publisher
Blackwell Science, London
Publication country
United Kingdom
Document type
Article
Language
English
Author keyword
CYP2C19 CYP2D6 Swedes adverse effect antidepressant citalopram enantiomers genotype mania mephenytoin metabolic ratio metabolism metabolites pharmacokinetics phenotype stereoisomerism yawning
Keyword (fr)
Citalopram Cytochrome P450 Débrisoquine Enantiomère Génotype Génétique Homme Individu sain Isozyme Méphénytoïne Métabolisme Pharmacocinétique Pharmacogénétique Phénotype Polymorphisme Psychotrope Stéréoisomère Stéréosélectivité Cytochrome CYP2C19 Cytochrome CYP2D6 Antidépresseur Inhibiteur recapture Sérotonine
Keyword (en)
Citalopram Cytochrome P450 Debrisoquine Enantiomer Genotype Genetics Human Healthy subject Isozyme Mephenytoin Metabolism Pharmacokinetics Pharmacogenetics Phenotype Polymorphism Psychotropic Stereoisomer Stereoselectivity Antidepressant agent Reuptake inhibitor Serotonin
Keyword (es)
Citalopram Citocromo P450 Debrisoquina Enantiómero Genotipo Genética Hombre Individuo sano Isozima Mefenitoína Metabolismo Farmacocinética Farmacogenética Fenotipo Polimorfismo Psicotropo Estereoisómero Estereoselectividad Antidepresor Inhibidor recaptura Serotonina
Classification
Pascal
002 Biological and medical sciences / 002B Medical sciences / 002B02 Pharmacology. Drug treatments / 002B02B Neuropharmacology / 002B02B02 Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)

Francis
770 Psychology. Psychoanalysis. Psychiatry / 770-E Psychopharmacology

Discipline
Pharmacological treatments Psychopathology. Psychiatry. Clinical psychology
Origin
Inist-CNRS
Database
FRANCIS ; PASCAL
INIST identifier
15114750

Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS

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