Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer
- Author
- GRADY, William M1 ; WILLIS, Joseph2 ; KIM, Seong-Jin9 ; MARKOWITZ, Sanford1 10 6 ; GUILFORD, Parry J3 ; DUNBIER, Anita K3 ; TORO, Tumi T3 ; LYNCH, Henry4 ; WIESNER, Georgia5 6 ; FERGUSON, Keely2 ; ENG, Charis7 ; PARK, Jae-Gahb8
[1] Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, United States
[2] Department of Pathology, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, United States
[3] Cancer Genetics Laboratory, Department of Biochemistry, University of Otago, Dunedin, New Zealand
[4] Department of Preventive Medicine, Creighton University Medical School, Omaha, Nebraska, United States
[5] Department of Human Genetics, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, United States
[6] Ireland Cancer Center, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, United States
[7] Clinical Cancer Genetics and Human Cancer Genetics Programs, Comprehensive Cancer Center, and Division of Human Genetics, Department of Internal Medicine, Ohio State University Medical School, Columbus, Ohio, United States
[8] Department of Surgery, Seoul National University Hospital, Seoul, Korea, Republic of
[9] Laboratory of Cell Regulation and Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland, United States
[10] Howard Hughes Medical Institute, Cleveland, Ohio, United States - Source
Nature genetics. 2000, Vol 26, Num 1, pp 16-17 ; ref : 15 ref
- Publisher
- Nature Publishing Group, London
- Publication country
- United Kingdom
- Document type
- Article
- Language
- English
- Keyword (fr)
- Cadhérine E Estomac Expression génique Homme Méthylation Promoteur transcription Tumeur Gène CDH1 Appareil digestif pathologie Estomac pathologie Maladie héréditaire Protéine CAM
- Keyword (en)
- E Cadherin Stomach Gene expression Human Methylation Transcription promoter Tumor Digestive diseases Gastric disease Genetic disease Cell adhesion molecule
- Keyword (es)
- Cadherina E Estómago Expresión genética Hombre Metilación Promotor transcripción Tumor Aparato digestivo patología Estómago patología Enfermedad hereditaria Proteína CAM
- Classification
- Pascal
- 002 Biological and medical sciences / 002B Medical sciences / 002B13 Gastroenterology. Liver. Pancreas. Abdomen / 002B13B Stomach. Duodenum. Small intestine. Colon. Rectum. Anus / 002B13B01 Tumors
- Discipline
- Gastroenterology. Liver. Pancreas. Abdomen
- Origin
- Inist-CNRS
- Database
- PASCAL
- INIST identifier
- 1512359
Sauf mention contraire ci-dessus, le contenu de cette notice bibliographique peut être utilisé dans le cadre d’une licence CC BY 4.0 Inist-CNRS / Unless otherwise stated above, the content of this bibliographic record may be used under a CC BY 4.0 licence by Inist-CNRS / A menos que se haya señalado antes, el contenido de este registro bibliográfico puede ser utilizado al amparo de una licencia CC BY 4.0 Inist-CNRS
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DOI
10.1038/79120 
https://dx.doi.org/10.1038/79120
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